PhenoImager® Fusion
The PhenoImager ® ; Fusion system is a whole-slide, single-cell resolution, ultrafast multispectral imager ideal for standard throughput brightfield and fluorescence imaging applications. This imaging platform can be integrated with the PhenoCycler ® ; system (formerly CODEX ® ) for ultra high-plex spatial discovery at scale.
PhenoImager™ Fusion
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Capable of both brightfield and fluorescence whole-slide imaging, the PhenoImager Fusion instruments serves the needs of laboratories with standard throughput needs while still delivering high quality imaging with fast scanning times. Combined with our proprietary Multispectral Imaging (MSI) Technology (patent pending) which allows for easy detection and the measurement of multiple overlapping biomarkers within a single tissue without the interference of autofluorescence and fluorophore crosstalk, the PhenoImager Fusion provides you with confidence to accurately phenotype and quantify tumor-immune cell interactions in the tissue microenvironment (TME) and develop biomarker signatures with higher predictive accuracy.
Spatial phenotyping without compromise in plex, resolution, or throughput
Biological systems are complex, and full spatial understanding of tissue heterogeneity and cellular microenvironments has been hampered by trade-offs that are forced by the available analytical technologies.
All of which has given rise to the concept of the ‘iron triangle’ – the hard problem of improving resolution, plex and throughput simultaneously in one analytical solution.
But the world is set to change with the advent of new spatial phenotyping approaches that enable viewing, characterization and quantification of cells by lineage and variant with single-cell resolution, all in the context of an intact tissue sample.
From capturing tumor heterogeneity and validating cancer models, to teasing out how the cellular microenvironment impacts disease progression and treatment response, this guide will explain how spatial phenotyping can deliver advances in automation, efficiency, tunability, and speed that are set to transform how we study tissue biology.
