Products & ReviewLife Sciences
PD-L1 (CD274）
Recombinant Human Programmed Death-Ligand 1 (PD-L1/CD274/B7-H1), the primary ligand for PD-1, expressed on tumor and immune cells to suppress anti-tumor immunity.
PD-L1 (CD274）
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Description
PD-L1 is often upregulated on many cancer cells, allowing them to evade immune attack by engaging PD-1 on T-cells. Its expression is a key biomarker for response to checkpoint blockade therapy. Our PD-L1 protein is vital for screening inhibitory antibodies, developing diagnostic tests, and studying the PD-1/PD-L1 axis.
Key Features & Benefits:
- High Purity and Correctly Folded Extracellular Domain
- Binds PD-1 with High Affinity
- Suitable for IHC Control and Diagnostic Development
- Multiple Isoforms and Formats Available
Relevant Applications:
- Anti-PD-L1 Therapeutic Antibody Screening
- Companion Diagnostic Assay Development and Validation
- Cancer Immunology and Immune Evasion Research
- Binding and Blocking Assays
