Membrane Proteins Expression and Purification
Specialized services for the challenging production of functional, stabilized membrane proteins, including GPCRs, ion channels, and transporters, for structural and drug discovery.
Membrane Proteins Expression and Purification
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Membrane proteins are notoriously difficult to produce due to their hydrophobicity and instability in solution. Our service leverages advanced expression systems (e.g., insect, mammalian) and purification strategies (detergents, nanodiscs) to deliver functional, monodisperse membrane proteins suitable for the most demanding applications.
Key Features & Benefits:
- Expertise in GPCR, Ion Channel, and Transporter Production
- Stabilization in Detergents, Liposomes, or Nanodiscs
- Functional Validation via Binding or Activity Assays
- Support for Cryo-EM and Structural Biology Projects
Relevant Applications:
- High-Throughput Screening for Drug Discovery
- Structural Biology (X-ray Crystallography, Cryo-EM)
- Antibody Discovery against Membrane Targets
- Biophysical Characterization (SPR, ITC)
