Lentivirus Gene Expression Vector
Lentivirus Gene Expression Vector
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The lentiviral vector system is a highly efficient vehicle for introducing genes permanently into mammalian cells. Presently, it is one of the two most commonly used methods for gene delivery into mammalian cells (the other being conventional plasmid transfection). Features that make this system so popular include the ability to choose which promoter will drive the gene of interest and the ability to infect a very wide range of cell types.
Lentiviral vectors are derived from HIV, which is a member of the retrovirus family. Wildtype lentivirus has a plus-strand linear RNA genome.
