In Vitro ADME/DMPK Studies
With decades of drug metabolism, drug-drug interactions (DDI) and related expertise, BioIVT’s experts can provide you with the right studies to understand the properties and potential risks of your compound when it’s most critical for your program.
Drug Metabolism and Interaction Assays
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BioIVT's comprehensive ADME services combine the expertise of XenoTech, Cypex, ZenBio and others to provide a full spectrum of drug metabolism, drug-drug interactions (DDI), and related assays, bioanalysis or consulting services, tailored to your therapeutic, stage of development and program goals. Available services include:
- Metabolite ID/Characterization
- Metabolic Stability
- Reaction Phenotyping
- Transporter Inhibition & Substrate
- Enzyme Inhibition & Induction
- Cell Permeability
- RBC Partitioning & Plasma Protein Binding
- Lysosomal Trapping
- Hepatotoxicity
- Hepatobiliary Disposition
- Antioxidant Assays
- Bioanalysis
- Consulting (Gap Analysis, Due Diligence, Writing/Presentations, etc.)
- And more
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Isolated Immune Cells
BioIVTIsolated immune cells play a crucial role across the stages of drug discovery and development from biomarker and target identification through screening and safety assessment to manufacturing. They can be used to create disease models, cell lines, gene editing techniques and more.
RUO and GMP Leukopaks
BioIVTBioIVT offers high quality, normal and disease state, fresh mobilized and cryopreserved leukopaks, custom collected or sourced from extensive inventory, featuring a diverse donor pool including over 600 HLA-typed recallable, consented donors near biotech hubs in the US and UK.
In Vitro ADME-Tox Test Systems
BioIVTBioIVT is the leading provider of quality, highly characterized, ethically procured ADME research products, featuring custom preparation or extensive ready-to-ship inventory, large lot sizes and expert support.