In Vitro ADME/DMPK Studies
With decades of drug metabolism, drug-drug interactions (DDI) and related expertise, BioIVT’s experts can provide you with the right studies to understand the properties and potential risks of your compound when it’s most critical for your program.
Drug Metabolism and Interaction Assays
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BioIVT's comprehensive ADME services combine the expertise of XenoTech, Cypex, ZenBio and others to provide a full spectrum of drug metabolism, drug-drug interactions (DDI), and related assays, bioanalysis or consulting services, tailored to your therapeutic, stage of development and program goals. Available services include:
- Metabolite ID/Characterization
- Metabolic Stability
- Reaction Phenotyping
- Transporter Inhibition & Substrate
- Enzyme Inhibition & Induction
- Cell Permeability
- RBC Partitioning & Plasma Protein Binding
- Lysosomal Trapping
- Hepatotoxicity
- Hepatobiliary Disposition
- Antioxidant Assays
- Bioanalysis
- Consulting (Gap Analysis, Due Diligence, Writing/Presentations, etc.)
- And more
