Products & ReviewLife Sciences
GPCRs Proteins
Active, stabilized G-Protein Coupled Receptors (GPCRs), prepared in native-like conformations, for high-throughput screening, ligand binding studies, and structure-based drug discovery.
GPCRs Proteins
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Description
GPCRs are a large family of membrane proteins that are major drug targets. Working with them is challenging due to their instability outside the cell membrane. This portfolio offers GPCRs stabilized in detergent micelles or nanodiscs, making them ideal reagents for biochemical and biophysical assays.
Key Features & Benefits:
- Stabilized in Active or Inactive Conformations
- High Purity and Monodispersity
- Compatible with Binding (SPR) and Functional Assays
- Broad Coverage of Class A, B, and C GPCRs
Relevant Applications:
- High-Throughput Screening for GPCR Agonists/Antagonists
- Ligand Binding Affinity and Kinetics Studies (SPR)
- Antibody Discovery against Complex Membrane Targets
- Structural Biology and Cryo-EM Studies
