GloMax® Explorer Multimode Microplate Reader

  The Quantus™ Fluorometer is an easy-to-use and affordable single-tube fluorometer.   The highly sensitive instrument is preprogrammed with QuantiFluor® Dye protocols for single-stranded DNA, double-stranded DNA and RNA quantitation but is also compatible with other fluorescent assays. Quantus™ Fluorometer does the math for you and displays your concentration after each measurement automatically. No computer is required. The Quantus™ Fluorometer will save and display the 20 most recent measurements. However, the fluorometer can be connected to a computer to transfer data in real time. Quantus™ Fluorometer Features: High Performance - Integrated with QuantiFluor® Dyes for high sensitivity, broad dynamic range and target specificity. Great for low-level sample quantitation such as FFPE or viral samples. Increased Sensitivity - Significantly increased sensitivity over absorbance at 260nm (NanoDrop®) for those samples that are low in concentration. Ten times more sensitive than Qubit® 2.0. A detection limit of 50pg/ml, compared to 500pg/ml for the Qubit® 2.0. With a customized low standard curve, the detection limit can read as low as 1pg/ml. Easy-to-Use Workflow and Navigation - Flexible with custom protocols and user-defined settings. PC software for data management workflow. Affordable Price - Cost-effective to easily incorporate into your laboratory.

  The mass spectrometry-compatible yeast and human protein extracts are designed specifically for mass spectrometry applications.   The extracts are predigested and cleaned up by solid-phase extraction for immediate use in liquid chromatography/mass spectrometry (LC/MS) analysis. Both the yeast and human extracts also are available in an intact undigested form to provide a test material for optimizing mass spec protein sample preparation. The yeast extracts are beneficial for users who prefer working with a relatively compact and well studied proteome, whereas the human extract provides opportunity for working with a complex proteome having a large dynamic range. Consistent extract protein composition is ensured by tight control over cell culture conditions and manufacturing process. Lot-to-lot consistency of extracts is monitored by various protein and peptide qualitative and quantitation methods, including LC/MS and amino acid analysis (Table 1). Our manufacturing process assures compatibility with reverse phase liquid chromatography and mass spectrometry by monitoring nonspecific protein fragmentation, nonbiological post-translational modifications and, for digested extracts, minimal undigested peptides. Features & Benefits: Compatible with LC/MS instrumentation platforms. Minimal nonbiological post-translational modifications. Peptide quantity measured by AAA. Model systems for method development/instrument monitoring. Multiple formats (digest/intact).

A Complete Solution for Monitoring LC and MS Instrument Quality Control and Performance. In combination with an accompanying software tool, the 6 × 5 LC-MS/MS Peptide Reference Mix provides a convenient way to assess LC column performance and MS instrument parameters, including sensitivity and dynamic range. Consists of 30 peptides; 6 sets of 5 isotopologues of the same peptide sequence, differing only in the number of stable, heavy-labeled amino acids incorporated into the sequence Labels are uniform 13C and 15N atoms. Isotopologues are chromatographically indistinguishable; however, since they differ in mass, they are clearly resolved by mass spectrometry. The isotopologues of each peptide are present in a series of tenfold dilutions. This format allows assessment of instrument dynamic range and sensitivity from a single run. The 6 × 5 LC-MS/MS Peptides are AAA-qualified for accurate monitoring, and are compatible with multiple applications and neat or complex mixtures.