Forensic Toxicology Screening Solution with UNIFI
Purpose-built Solution Achieves Reliable Results with Unparalleled Efficiency and Accuracy The Forensic Toxicology Screening Application Solution with UNIFI delivers the sensitivity, reproducibility, and ease-of-use necessary to perform broad screening techniques on complex biological samples to identify drugs of abuse and other toxicants of interest. Now, for the first time, you will be able to reliably report the presence o…
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Purpose-built Solution Achieves Reliable Results with Unparalleled Efficiency and Accuracy
The Forensic Toxicology Screening Application Solution with UNIFI delivers the sensitivity, reproducibility, and ease-of-use necessary to perform broad screening techniques on complex biological samples to identify drugs of abuse and other toxicants of interest. Now, for the first time, you will be able to reliably report the presence or absence of toxicological compounds of interest, easily streamline workflows, and increase the speed of analysis for complex matrices using the scientific library functionality and flexible reporting templates.
Capture, process and analyze complex high-end mass spectrometry and chromatography data on a single software platform. Gain the ability to test and confirm the presence of compounds in a single measurement. Drastically increase workflow efficiency and improve data review and reporting time with pre-defined workflows. Transform your laboratory with the most innovative screening solution ever built for forensic toxicology testing.
Forensic Toxicology Screening Solution with UNIFI Features:
- Reliably detect and report the presence of drugs and other compounds of interest, while minimizing both false positive and negative results
- Identify known and unknown compounds with the UNIFI Toxicology Scientific Library
- Build a historical record of sample analysis data for retrospective review as new challenges emerge
- Ensure compliance with best-in-class data security and traceability
Analysis of Plant Alkaloids Through Accurate Mass Screening and Discovery
Plant alkaloids are nitrogen containing compounds derived from plant material. They have been used for centuries for medicinal and recreational purposes. Time of flight mass spectrometry can accurately identify substance composition and allow for in depth study of chemical structures. This application note describes a study using the Waters ACQUITY UPLC I-Class to analyze plant alkaloids and create an alkaloid library for future reference.
Using the Waters Forensic Toxicology Screening Application Solution with UNIFI to Determine Diuretics in Urine
Diuretics are a class of pharmaceutical compounds whose primary aim is to promote urine production. They can also be used to mask the presence of banned or illegal substances by facilitating dilution of the urine and aiding excretion. Consequently the use of diuretics is prohibited for athletes by the World Anti-Doping Agency (WADA). However, a number of diuretics only ionise in negative electrospray mode (ESI-). This application note investigates methods to further extend the Forensic Toxicology Screening Application Solution with UNIFI to include compounds that ionise in negative mode and to use the method to determine the presence of diuretics in urine, particularly at concentrations below the WADA MRPL.
Analysis of Beta-Blockers Using UPLC with Accurate-Mass Screening
The World Anti-Doping Agency (WADA) includes beta-blockers in its 2014 Prohibited List (Category P2). Recent advances in liquid chromatography and mass spectrometry can help determine the presence of beta-blockers in urine. The Waters Forensic Toxicology Application Solution with UNIFI® enables analysts to confidently screen and identify beta-blocker drugs in urine; data is processed automatically and presented to the user with fully customizable workflows and reports.
