FabULOUS® (SpeB)
FabULOUS (SpeB) is a recombinantly produced cysteine protease that under reduced conditions digests in the hinge region of antibodies from many species and subclasses, including human, mouse, rat and goat.
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FabULOUS (SpeB) is a recombinantly produced cysteine protease that under reduced conditions digests in the hinge region of antibodies from many species and subclasses, including human, mouse, rat and goat. FabULOUS is available in two product formats: as a lyophilized powder (FabULOUS Enzyme) and as a lyophilized powder in a kit together with affinity spin columns (FabULOUS Fab kit), for easy preparation and purification of Fab fragments from mouse IgG.
FabULOUS Primary Digestion Site:
- Human IgG1 ..KTHT / CPPCPAPEL..
- Mouse IgG1 ..KPCIC / TVPEVS..
The molecular weight of FabULOUS is 28 724 Da and the enzyme contains a His-tag.
