ExD Cell for LC/Q-TOF
Quadrupole Time of Flight LC/MS
Agilent ExD cell and Agilent 6545XT AdvanceBio LC/Q-TOF
CID, ECD, or both
The electromagnetostatic ExD cell
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The Agilent ExD cell is an add-on for the Agilent 6545XT AdvanceBio LC/Q-TOF which enhances the platform's abilities to characterize peptides and proteins by introducing electron capture dissociation (ECD). ECD is an additional technique for molecular fragmentation, complementary to collision-induced dissociation (CID). With the ExD cell, the system gains the capability to fragment intact proteins from the top down, distinguish isobaric residues through side-chain fragments, and produce informative fragments while preserving fragile modifications like glycosylation and phosphorylation.
The ExD cell's high ECD efficiency extends its functionality to analytes with lower charges (≥2+), overcoming a historical constraint for electron dissociation techniques. When combined with the benefits of the 6545XT, like ultrahigh vacuum and quadrupole isolation up to 4,000 m/z, it also becomes an ideal choice for top- and middle-down characterization of larger proteins.
Currently not available in Korea.
Introducing the new Agilent ExD cell for Agilent 6545XTLC/Q-TOF
Discover the new Agilent ExD cell, an add-on for the Agilent 6545XT AdvanceBio LC/Q-TOF which enhances the platform's abilities to characterize peptides and proteins by introducing electron capture dissociation (ECD). With the ExD cell, the system gains the capability to fragment intact proteins from the top down, distinguish isobaric residues through side-chain fragments, and produce informative fragments while preserving fragile modifications like glycosylation and phosphorylation.
