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CLIP-Seq technology

A service to identify the RNA targets of RNA-binding proteins (RBPs) on a genome-wide scale, providing insights into post-transcriptional regulatory networks.

Creative BioMart

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Description

Cross-Linking and Immunoprecipitation (CLIP) followed by high-throughput sequencing maps the exact binding sites of an RBP to its RNA targets in vivo. This powerful technique reveals how RBPs influence RNA splicing, stability, localization, and translation, which is crucial for understanding gene regulation in health and disease.

Key Features & Benefits:

  • Genome-Wide Mapping of RBP Binding Sites
  • High Resolution and Specificity
  • Identification of Direct vs. Indirect Interactions
  • Bioinformatics Analysis for Pathway Enrichment

Relevant Applications:

  • Discovery of RBP Function and Mechanisms
  • Studying Post-Transcriptional Gene Regulation
  • Cancer Biology and Neurological Disorder Research
  • Viral-Host Interaction Studies

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