ARM-D® Kit, β-Lactamase
The Streck ARM-D Kit, β-Lactamase is a multiplex real-time PCR kit for the rapid detection of β-lactam antibiotic resistance genes in Gram-negative bacteria. This comprehensive kit allows you to detect over 450 allelic variants in 9 clinically relevant carbapenemases, extended-spectrum beta-lactamases (ESBLs) and plasmid-mediated ampC gene families, KPC, NDM, OXA-48, IMP, VIM, DHA, CMY-2, CTX-M-14 and CTX-M-15.
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The ARM-D Kit, β-Lactamase is part of a family of comprehensive, multiplex real-time PCR kits that detect over 1,000 antimicrobial resistance (AMR) gene variants from 26 different gene target families. Streck ARM-D Kits provide a rapid detection strategy for monitoring β-lactam antibiotic resistance. With these kits, your lab can improve surveillance, aid antibiotic stewardship programs and support infection control programs. These kits have a high degree of sensitivity and specificity, providing you accurate, reliable results. Every kit includes positive controls for each gene target to monitor analytical process as well as an endogenous internal control (16SrRNA gene) to reduce false negatives due to PCR inhibition, DNA degradation or poor extraction.
All Streck ARM-D kits are compatible with most 4-channel real-time thermal cyclers. An amplification protocol and analysis guide are available for the following instruments: Applied Biosystems™ 7500 Fast and 7500 Fast Dx, QuantStudio™ 7Flex, Bio-Rad CFX96 Touch™ and QIAGEN Rotor-Gene® Q.
Features
- Detects over 450 allelic variants in the KPC, NDM, OXA-48, IMP, VIM, DHA, CMY-2, CTX-M-14 and CTX-M-15 gene families
- Compatible with most 4-channel real-time PCR thermal cyclers
- Protocol can be completed in less than one hour
- Contains positive controls for each gene target
- Includes a premixed 2X master mix (DNA Polymerase, dNTPs, MgCl2 and reaction buffer)
Benefits
- Detects gene variants not covered by cartridge-based kits
- Identifies resistance mechanisms before susceptibility results are available
- High degree of sensitivity and specificity ensures reliable and accurate results
- Reduced cost per sample compared to cartridge-based methods
- For Research Use Only. Not for use in diagnostic procedures.
Validation of the Streck β-Lactamase kit for screening bacterial isolates
In this video, Flor Hudson, microbiologist for the City of Houston public health lab, discusses the validation of the Streck β-Lactamase kit for screening bacterial isolates. The ARM-D® Kits, providing a rapid detection strategy, aim to enhance antibiotic resistance monitoring for improved AMR surveillance, antibiotic stewardship programs, and infection control. These real-time PCR kits offer comprehensive detection of gene variants not covered by cartridge-based methods, including genes encoding carbapenemases, extended-spectrum β-lactamases, plasmid-mediated ampCs, and other emerging threats.
