Products & ReviewLife Sciences
ADC Target Protein
Recombinant proteins representing well-validated antigens for Antibody-Drug Conjugates (ADCs), facilitating the screening, characterization, and development of these targeted oncology therapeutics.
ADC Target Protein
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Description
ADC target proteins are tumor-associated antigens that are overexpressed on cancer cells. They are used to select and optimize the antibody (mAb) component of an ADC, which delivers a potent cytotoxic drug specifically to the cancer cell. The quality of these proteins is crucial for generating effective and specific ADCs.
Key Features & Benefits:
- High Purity and Native-like Conformation
- Extracellular Domains with Preserved Epitopes
- Ideal for Antibody Screening and Affinity Measurement
- Low Endotoxin for In Vitro Functional Assays
Relevant Applications:
- Hybridoma and Phage Display Screening
- Antibody Affinity and Specificity Characterization
- Internalization and Payload Delivery Studies
- ADC Potency and Mechanism-of-Action Assays
