6545XT AdvanceBio LC/Q-TOF
The Agilent 6545XT AdvanceBio LC/Q-TOF system is designed to handle multiple workflows in biopharmaceutical characterization. When you need to access the most detailed information at the intact protein level, automatically confirm protein sequence at the peptide level, and confidently understand post-translational modifications, the 6545XT AdvanceBio Q-TOF delivers results you can trust.
Good and reliant instrument for Biopharma applications
Mass Spectrometry
Good software for relatively easy operation (for a mass spectrometer). Software to analyze biopharma data is unflexible, and has room to improve. After salescare by Agilent is good, and online support is fast (within 24h). The instrument delivers consistent results, calibration is quite stable but sensitive to temperature shifts. Good value for money.
Review Date: 2 Feb 2024 | Agilent Technologies
The Agilent 6545XT AdvanceBio LC/Q-TOF system is designed to handle multiple workflows in biopharmaceutical characterization. When you need to access the most detailed information at the intact protein level, automatically confirm protein sequence at the peptide level, and confidently understand post-translational modifications, the 6545XT AdvanceBio Q-TOF delivers results you can trust.
Features:
- Get up and running fast with quick-start methods that include Agilent AdvanceBio LC columns for intact protein and peptide workflows.
- Characterize both major and minor intact protein variations with an automated data workflow featuring MassHunter BioConfirm software.
- Adapt your instrument to your needs with SWARM autotune to ensure optimum performance with no manual adjustment. New large molecule setting provides sub-nanogram detection levels for intact glycosylated monoclonal antibodies.
- Be sure of your results with mass accuracies within 10 ppm for glycosylated intact proteins.
- Dig deeper into your digested samples with the powerful new iterative MS/MS feature.
- Maximize your uptime with a system tested to perform through thousands of protein injections without degradation of performance.
- Minimize maintenance delays with vent-free cleaning of entrance optics.





















