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Zymo Research partners with Tecan for COVID-19 viral RNA extraction

Zymo Research

The partnership aims to launch a ready-to-go processing solution that streamlines viral DNA/RNA extraction

2 Apr 2020
Diane Li
Assistant Editor

Industry news

Zymo Research has announced a partnership with Tecan to launch a ready-to-go processing solution to streamline viral DNA/RNA extraction from nasopharyngeal swabs, oropharyngeal swabs, saliva, sputum, plasma, and serum. The DreamPrep™ NAP workstation, featuring Zymo Research’s Quick-DNA/RNA™ Viral MagBead Kit, simplifies the process by providing pre-loaded scripts, optimized for viral RNA extraction, that are currently being validated for COVID-19 assays by high complexity testing labs.

As the COVID-19 pandemic expands, laboratories are scaling up testing using high-throughput automated workflows to isolate the viral RNA for subsequent detection. These workflows typically require time-consuming scripting, configuration, and optimization for the nucleic acid extraction to function properly, which can dramatically decrease lab scalability in this critical time.

“Nucleic acid extractions can be one of the most challenging, frustrating, and time-consuming portions of a workflow to automate,” said Ryan Kemp, Director of Nucleic Acid Solutions at Zymo Research. “With push-to-start sample purification, the DreamPrep™ NAP workstation is uniquely positioned to help labs around the world quickly and effectively scale their testing to accommodate a much larger number of tests and ultimately mitigate the spread of the virus.”

Kemp notes, “We understand the need to rapidly respond to the COVID-19 pandemic and have dramatically increased our supply of the Quick-DNA/RNA™ Viral MagBead extraction kits. Additionally, we have expanded our team of technical experts to help with the global effort. Both Zymo Research and Tecan are giving the highest priority to assist researchers who are extracting viral RNA using the DreamPrep™ NAP workstation.”

In the past year, Zymo Research and Tecan have worked together to optimize magnetic bead-based extraction of viral RNA using the cutting-edge DreamPrep™ NAP workstation. The result of this collaboration is a preprogrammed, preconfigured, load-and-go system that is optimized for high-throughput viral RNA extraction. The workstation features a user-friendly interface and guided setup to streamline implementation.

“By combining the Zymo Research optimized extraction kits with our easy-to-use liquid handling platform, we have delivered a complete viral processing solution with the DreamPrep™ NAP workstation,” said Beatrice Marg-Haufe, Product Manager at Tecan. “In this challenging climate, we are working very closely with Zymo Research to enable scientists to respond to this pandemic quickly.”

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Quick-DNA™ HMW MagBead Kit

Zymo Research

The Quick-DNA™ HMW MagBead Kit is the easiest method for high molecular weight total DNA extraction (e.g., genomic, mitochondrial, viral) from any biological fluid, cell culture, solid tissue, or environmental sample. Innovative reagents and Zymo Research’s unique system allow for a simple Bind, Wash, & Elute procedure that is unmatched in providing ultra-pure and high yield DNA of > 150 kb size. Isolated DNA is ready for immediate use in sensitive downstream applications including long read (Oxford Nanopore™) and NGS sequencing, qPCR, arrays, and methylation analysis. The Quick-DNA™ HMW MagBead Kit facilitates rapid and efficient purification of high molecular weight DNA from any sample by combining enzymatic and chemical extraction regimens. Features: High Molecular Weight DNA: Extract high molecular weight DNA up to 150 kb from any sample Ultra-Pure: Highest DNA yield and purity equipped with RNA removal technology Third-Generation Sequencing Ready: Optimized for long read sequencing (including Oxford Nanopure™ and PacBio SMRT sequencing™) 

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Sample ManagementSample management systems include sample storage devices such as freezers and plate storers, sample environment enclosures and sample organization, retrieval and sorter systems. Useful system features include high-throughput, automation, robotic arms, automated liquid handling and associated database systems. Accessories in sample management include barcode scanners, heat sealers and tubes.DNA / RNA Extraction and PurificationPurified DNA and RNA are required for numerous downstream molecular biology applications. Consequently, the importance of high-quality DNA/RNA extraction and purification equipment cannot be underestimated. Many purification kits are available and are typically optimized for nucleic acid type and source, including plasmid DNA, genomic DNA, mRNA, RNA and viral nucleic acid purification kits. Automated extraction and purification of nucleic acids can be implemented with magnetic bead separator instruments or high-throughput purification workstations. Find the best DNA/RNA extraction and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Robotic WorkstationsRobotic workstations are automated platforms enabling the user to perform high-throughput, multi-application processes, from sample preparation tasks such as PCR set-up, DNA purification and NGS library preparation, to integrated sample prep and analysis workstations. Automation makes processes consistent, fast, precise and fully walk-away. Find the best robotic workstations in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Automated Liquid HandlingAutomated liquid handling equipment is used to mix, dilute and dispense allotted volumes of liquid into microplates and other vessels automatically. The robotic, liquid handling arms can dispense from single channel to 3456 multichannel as well as operate nanoliter dispensing, enabling high throughput of samples. Find the best automated liquid handlers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DNA ExtractionDNA extraction is a critical step in many biological studies, including genomics, diagnostics, and forensic analysis. The process involves isolating DNA from cells or tissues, and the quality and purity of the extracted DNA can impact downstream applications. Explore DNA extraction products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.AutomationAutomation in laboratories and manufacturing processes enhances efficiency, precision, and scalability by reducing the need for manual intervention. It plays a critical role in improving productivity, minimizing human error, and accelerating workflows in fields like diagnostics, drug development, and industrial testing. Automation technologies include robotic systems, automated liquid handlers, and process control systems that streamline complex tasks and ensure consistent, reproducible results. Explore our peer-reviewed product directory to discover the best automation solutions, compare options, read user reviews, and get prices directly from manufacturers.Respiratory InfectionsRespiratory infections are caused by pathogens such as bacteria, viruses, and fungi, leading to diseases like pneumonia, tuberculosis, and COVID-19. It is important to identify respiratory infections quickly in patients to ensure appropriate treatment and care, and to prevent sepsis. Browse our peer-reviewed product directory to find the best tools for respiratory infection detection, compare products, check reviews, and get pricing directly from manufacturers.Liquid Handling WorkstationLiquid handling workstations automate the process of sample preparation, improving accuracy and efficiency. These systems are essential for high-throughput applications in biological, chemical, and pharmaceutical research, reducing human error and increasing reproducibility. Workstations come equipped with robotic arms, pipetting tools, and other accessories to streamline lab workflows. Explore liquid handling workstations in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.High ThroughputHigh throughput experiments allow the simultaneous processing of several samples. This parallelization reduces the cost per experiment and increases reproducibility and output volume of data.VirusesViruses are microscopic pathogens that require a host cell to replicate. Understanding their structure, replication cycle, and impact on the immune system is crucial in developing effective treatments, vaccines, and diagnostic methods. Research continues to focus on emerging viral diseases and antiviral drug discovery. Explore solutions for virus research, detection, and treatment in our peer-reviewed product directory; compare products, check customer reviews, and get pricing directly from manufacturers.CoronavirusCoronaviruses are a large family of viruses that can cause illnesses ranging from the common cold to more severe diseases like COVID-19. Research into the biology, transmission, and treatment of coronaviruses has become a global priority, particularly since the emergence of SARS-CoV-2. Understanding the virus�s structure and behavior is essential for developing vaccines, diagnostics, and antiviral treatments. Explore our peer-reviewed product directory to discover the latest research tools, diagnostic tests, vaccines, and treatments for coronavirus, compare products, read reviews, and receive pricing directly from manufacturers.Infectious DiseasesInfectious diseases are caused by pathogens such as bacteria, viruses, and fungi. Effective detection, prevention, and treatment are crucial to control outbreaks and improve public health. Diagnostic tools, vaccines, and antimicrobial treatments are essential components of managing these diseases. Research into emerging pathogens and resistance patterns continues to evolve. Browse our peer-reviewed product directory to find the best diagnostic tools, prevention solutions, and treatment options; compare products, read customer reviews, and get pricing directly from manufacturers.

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