Zinsser Analytic to Present New Solutions for Protein Crystallisation & Low Cost Vial Capping at MipTec 2010

14 Sept 2010
Sarah Sarah
Marketing / Sales

Product news

Zinsser Analytic will be presenting new products including the ProCrys Meso for protein crystallisation of membrane proteins, the SOPHAS Hy workflow for batch and continuous flow synthesis and the TraySy and Taris for low cost systems for vial filling, taring and capping.

Zinsser Analytic has made its name for innovative product development:
• Powder / solid handling
• Weighing
• Heating/Cooling/Mixing
• Capping/Decapping of screw and crimp caps
• Viscous media dispensing
• Filtration & Solid Phase Extraction (SPE)
• Sonication for dissolving & cleaning
• Pipetting & dissolution under inert atmosphere
• pH monitoring & titration
• Integrated analysis (LC, HPLC, GC, Density-, Viscosity Measurement)
• Inline solubility control
• Image analysis for workflow monitoring
… executed with our clever WinLissy software.

New members of product family:
• ProCrys Meso for Protein Crystallisation of Membrane Proteins
• SOPHAS Hy – workflow for batch & continuous flow synthesis including synthesis preparation & workup on one platform
• LISSY for QuEChERs – for fast analysis in the food industry
• SOPHAS Cat HT, a catalyst factory for catalyst screening and optimisation
• TraySy and Taris – low cost systems for vial filling, taring and capping

Come and meet us on booth H55.

LISSY

Zinsser Analytic GmbH

Sample preparation for a wide range of analysis types, sample dissolution, serial dilutions, reformatting steps and much more can be fully automated with Zinsser’s flexible liquid handling system, LISSY. LISSY is available in various standard configurations: from 90cm up to 200cm in length, from 1 up to 16 pipetting probes, with or without integrated gripper for moving plates, individual tubes or tools, etc. As with all Zinsser Analytic systems, LISSY can be custom designed using your current tools or by developing new tools to suit your application. “A compact system capable of automating many applications” - this is a request that Zinsser Analytic is asked daily. Zinsser have developed a highly flexible concept, where modules on the workbench are mixed and matched to create the system configuration for the required applications, as typified by the workbench for a reformatting application, which can be easily adapted by the user for the specific reactor types that should be handled that day, offering the variety to reformat from big reactor blocks with inert gas supply and cooling, to small microtitre plates. If pipetting from flat bottom containers is required, a tilting station can also be installed on the workbench so that entire samples can be pipetted to the last drop. In addition to flexible workbenches, LISSY is also extremely versatile as regards the configuration of the liquid handling channels. Many applications can demand a diversity in pipetting probes in a single run – from probes for septum piercing to avoid evaporation, for sample filtration from the top, disposable tips for contamination-free pipetting, for handling corrosive reagents, for ion-free dispensing, for spotting of reagents, for spraying in defined angles to wash remaining samples off the walls or for applying pesticides or herbicides directly to plants. If an inert atmosphere is required, the liquid handling probes can also be equipped with an additional gas channel. All these situations are handled with ease, since each pipetting channel can be defined with a different type of tip and an individual pipetting volume. There is a vast range of different pipetting probes to choose from. LISSY, can be further equipped with additional modules such as sample identification (barcode reading), pH-measurement and adjustment, heating and cooling stations, vortexers and stirrers and many others. Should your requirements change in the future, LISSY can be upgraded with new tools and options as your workflows evolve. The hardware modules can be easily located and removed from the workbench so that the layout needed for today’s task can be easily configured prior to run. Zinsser’s user-friendly software, WinLissy, organises all layouts and methods for easy access and modification – a new layout can be created with the minimum of effort. So be ready for today’s and tomorrow’s tasks with our flexible automated, liquid handling systems and our user-friendly software.

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ProCrys Meso

Zinsser Analytic GmbH

Liquid Handling for Nanoliters and Microliters > ProCrys Meso, the new liquid handling platform for the preparation of Membrane Proteins Dealing with membrane proteins in lipidic meso-phases is not an easy task. Until now the sample preparation has been a very tedious and time-consuming task. Zinsser Analytic has developed ProCrys Meso, the new liquid handling platform for the preparation of 96 in-meso (or cubic phase) proteins. 1 meter liquid handling platform with 2 pipetting arms Accurate and precise dispensing of the protein and the screening solution Preparation of own screening solutions on the workbench An integrated module ensures the ideal humidity conditions for the process Precise and reproducible dispensing of the mesophase Positioning of the protein is controlled by a high precision laser. Sensor controlled shape and travel length of the needle of the protein dispenser.

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SOPHAS Hy

Zinsser Analytic GmbH

Automated Synthesisers - Speeding up the process of discovery and optimisation Zinsser Analytic and Thales Nano have combined forces in the development of a flexible synthesiser which offers traditional batch chemistry and modern continous flow chemistry including sample preparation and workup on one platform. The SOPHAS Hy system is an automatic system for synthesis and sample preparation that comprises liquid handling, heating, cooling and mixing functions with the continous flow chemistry reactor H-Cube and many optional tools to aid your synthesis such as powder handling, weighing, microwave-assisted synthesis, sonication and pH measurement & adjustment.

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Gas ChromatographyGas chromatography (GC) is an analytical technique used to separate and quantitate mixtures of small and volatile compounds. Gas chromatographs or GC systems include components such as GC columns, detectors, pumps and autosamplers. Choose from packed or capillary GC columns, flame ionization (FID), photoionization (PID) electron capture detectors and selective or non-selective detectors. Find the best gas chromatographs in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Baths and CirculatorsLaboratory baths and circulators are capable of refrigerating and heating to meet the demands of any temperature controlled application.Refrigerators Freezers and CryogenicsRefrigerators, Freezers & Cryogenics can be used for preservation or experimental purposes. Types of freezers include deep freeze, -80C°C, ultra-low temperature, explosion proof, cryogenic and controlled rate freezers. Freezing is also used in freeze-drying equipment for dehydration processes. Feature to consider in freezers include temperature control and recorders, failure alarms and self-closing mechanisms.FiltrationFiltration and microfiltration are used to separate solids, particulates or large molecules from fluids (liquid or gases) in order to purify the filtrate. Explore a range of filter formats, including filter paper, plates and membranes for your separation needs. While larger particulates may be separated by gravity filtration, smaller particulates may require additional force for timely separation. Microfiltration equipment includes vacuum filters, as well as positive pressure, crossflow and centrifugal filtration devices. Find the best filtration products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.pH Meters and ElectrodesIon and pH meters are electrochemical equipment used to measure the pH (acidity or alkalinity) or specific ion concentration of a solution. Other meters can also measure the conductivity or dissolved oxygen content of a solution. pH meters, specific ion meters, conductivity meters and dissolved oxygen meters can come as benchtop or portable equipment. A meter’s electrodes can be replaced with easy to clean electrodes or electrodes for difficult media. pH, ion and conductivity meters are typically used in life science research, pharmaceutical testing, food and beverage, environmental and water analysis. Find the best pH meters and electrodes in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Pipettes and DispensersPipettes and dispensers are essential lab equipment used to dispense measured volumes of liquid accurately. Explore a range of manual and electronic pipettes, including single and multichannel, serological and volumetric pipettes, as well as a range of pipette tips. Bottle-top dispensers are also available for simple and fast solvent dispensing. Find the best pipettes & dispensers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Solid-Phase ExtractionSolid-phase extraction (SPE) is used for clean-up, extraction and concentration of semi-volatile or non-volatile analytes from complex mixtures including blood, urine and food samples. Multiple formats are available for conducting SPE, including prepacked SPE cartridges, disks and microplates, as well as SPE sorbent powders for manual packing. SPE systems can be used to automate the process and extract multiple samples at once. Solid-phase microextraction (SPME) and supported liquid extraction (SLE) products are also available in the same formats. Find the best SPE, SLE and SPME equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Protein CrystallographyProtein crystallization is the process of crystallizing purified proteins for 3D structure analysis by x-ray crystallography. The main methods of protein crystallization include sitting drop, hanging drop and microbatch. It is important to control parameters such as pH, temperature and concentration. Following crystallization, detectors and software are used for data collection and analysis.pH and Conductivity MetersIon and pH meters, used for electrochemical techniques and measurements, measure the concentration of specific ions using electrodes (probes) and a meter. Features of ph and ion meters to consider include temperature compensation, auto-calibration, adjustable resolution, measurable range and accuracy. Meters can be handheld, portable, benchtop and modular.TitrationTitration is an analytical technique for determining substance concentration in a solution. For titration consider a manual or automated system, volumetric or coulometric reagent addition and indication by a potentiometer, spectrometer, turbidometer or by the Karl Fischer method. Other features of titration to consider include burettes, reagents, concentration range, reaction time and autosamplers.
Zinsser Analytic to Present New Solutions for Protein Crystallisation & Low Cost Vial Capping at MipTec 2010