Wyatt Technology to showcase first refractive index detector for UHPLC at Pittcon 2013

14 Feb 2013

Product news

Wyatt Technology Corporation will be showcasing its innovative new RI detector, the Optilab UT-rEX, on booth #2133 at PITTCON 2013, Philadelphia, PA, March 17- 21, 2013. The Optilab UT-rEX is specifically designed for use with UHPLC systems using columns packed with small beads.

The Optilab UT-rEX uses a combination of miniaturized components and cutting-edge semiconductor photodiode technology as well as proprietary computer algorithms and presents a host of instrument firsts.

Besides UV, mass spectrometry and evaporative light scattering, there has been no RI detector available for UHPLC applications until now. The linearity of the instrument over a wide range, coupled with its sensitivity to samples that are not UV active, make it an exciting addition to UHPLC.

Due to the extremely small volumes of UHPLC, the dead volume for the instrument is <1.5µl as compared to 10-20 µl for other RI detectors. As a result, the UT-rEX also offers superior resolution which will not be compromised. In addition to the instrument having no range or gain setting, the full range of instrument detection is always present and the full sensitivity exists over the entire range. The small flow cell and proprietary temperature regulation enable stable RI baselines and RIS signals which further enhance the detector’s sensitivity.

The Optilab UT-rEX can be operated below ambient temperatures as easily as above ambient. No hassle temperature control can be programmed down to 4°C or as high as 50°C. The Optilab UT-rEX is compatible with all UHPLC systems.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Refractive Index
Wyatt Technology to showcase first refractive index detector for UHPLC at Pittcon 2013