Wyatt Technology showcases the DynaPro NanoStar DLS Instrument at Pittcon 2013

21 Mar 2013
Sarah Thomas
Associate Editor

Product news

Wyatt Technology presented its latest Dynamic Light Scattering (DLS) instrument, the DynaPro® NanoStar® at booth #2133, PittCon 2013, March 17 – March, 2013 at the Pennsylvania Convention Center, Philadelphia, PA. The NanoStar has been created to deliver optimum versatility and stability for the non-invasive characterization of biomolecules and nanoparticles in solution.

Providing a number of advanced capabilities, the NanoStar surpasses the performance of conventional batch DLS instruments. Incorporating two distinctly dedicated light scattering detectors in its optical system, the NanoStar is capable of measuring both the hydrodynamic radius and absolute molecular weight of a sample simultaneously. The operating range of the detectors can be expanded by automatically attenuating the laser power from 10 to 100mW and adjusting a digital inline optical attenuator to achieve optimal signal level for the avalanche photo diode (APD).

The NanoStar offers a revolutionary temperature control capability for further characterization of nanoparticles over the widest range and at the most precise temperatures ever available in batch DLS. The system’s temperature control system provides a range from -15ºC to 150ºC, with a temperature stability of better than 0.01ºC over the entire range. The proprietary thermal design changes temperatures as fast as 15ºC/min, stabilizing at the temperature set point in minutes, with little overshoot, for the most precise thermal melt experiments possible.

The NanoStar employs a custom-designed correlator with a 100 nsec sampling time, which is fast enough to capture all of the dynamics of diffusing particles from fewer than 0.5 nm to over 1μm. A total of 512 bins provide simultaneous measurements of the autocorrelation function from 100 nsec to 1 hour. This guarantees that polydisperse samples with a wide range of molecular sizes are accurately measured.

The NanoStar can also be coupled with Wyatt’s DAWN® HELEOS® and miniDAWN™ TREOS® multi-angle light scattering (MALS) instruments for simultaneous on-line MALS and DLS characterization.

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ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.PittconPittcon is one of the largest conferences and exhibitions dedicated to laboratory science. It brings together professionals and innovators in analytical chemistry, physics, and biology, offering a platform to explore the latest scientific tools and technologies. From cutting-edge laboratory instruments to emerging research trends, Pittcon is a must-attend event for professionals in research and development. Dynamic Light ScatteringDynamic light scattering is used to measure the size distribution of particles in suspension by analyzing the way light scatters off them. It is commonly used in materials science, nanotechnology, and protein characterization. Browse our peer-reviewed product directory to find the best dynamic light scattering systems, compare products, check reviews, and get pricing directly from manufacturers.Protein BiologyThe analysis of protein expression, identity and function is vital for many areas of life science research and drug discovery. Some of the most commonly used techniques in protein analysis include Western blotting, electrophoresis and mass spectrometry.NanoparticlesNanoparticles are between 1-100nm in size. Nanoparticles can be used for a wide variety of applications including biomedical, catalysis and electronics.PolymersPolymers are large molecules made up of many repeat units. Natural polymers such as DNA and proteins are essential to life, whereas synthetic polymers such as polystyrene and polyethylene are used widely due to their functionality. Typical techniques for analysis include GPC, SEC, DSC, FT-IR and NMR.
Wyatt Technology showcases the DynaPro NanoStar DLS Instrument at Pittcon 2013