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Wyatt Technology will introduce the Eclipse DUALTEC at Pittcon 2013

21 Mar 2013
Sarah Thomas
Associate Editor

Product news

Wyatt Technology will introduce the Eclipse DUALTEC. Showcased at Pittcon 2013, Philadelphia, PA. This is the first commercial Field Flow Fractionation system using the Hollow-Fiber Flow-FFF (HF5) and Asymmetric Flow-FFF (AF4) technique - both integrated into one instrument, affording maximum flexibility in macromolecular and nanoparticle separations.

The DUALTEC is a further development of the already widely used AF4 technique, previously brought to instrumental perfection by Wyatt. AF4 is carried out by means of a flat channel and is used to separate macromolecules of various kinds. The DUALTEC represents a technological breakthrough because it provides the world's first commercial application of the hollow fiber separation technology. The hollow fiber is located in a cartridge and can be applied either as a multiple or as a disposable device. It is precisely this circumstance which paves the way for medical applications of this technology, such as in clinical diagnostics.

HF5 separation represents the optimum Flow-FFF method for low dead volume, high sensitivity, and short analysis time. HF5 is preferred for method development, because it takes minimal sample, time and solvent consumption. The Eclipse HF5 channel cartridge comes ready to use for more than a hundred injections, then it can be replaced by a fresh cartridge within seconds. Downtime is minimized, and there is no membrane to install or cleaning step required.

The Eclipse DUALTEC offers a routine method to complement size exclusion chromatography (SEC). The innovation of the Eclipse DUALTEC makes two different lines of separation available in one system. HF5 can be used on the same samples simply by flipping a software switch. In this way, AF4 is on stand-by as an orthogonal method to SEC, even in automated, unattended operation. The combination of HF5 and SEC is seamless. Two Flow-FFF methods-HF5 vs. AF4 flat channel-can be combined as well, allowing access to two different channel configurations.

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Size Exclusion ChromatographySize exclusion chromatography (SEC) is a liquid chromatographic technique used to separate and identify molecules based on their size, including polymers, proteins, nanoparticles & nucleic acid. SEC is further subdivided into gel filtration chromatography (GFC) and gel permeation chromatography (GPC) when an aqueous or organic mobile phase is used respectively. HPLC-based SEC systems and columns are available for analytical separation alongside SEC spin columns or filters to prep samples for many protocols. Find the best size exclusion chromatography equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Field Flow FractionationChromatographyChromatography is a powerful technique used to separate and analyze components of mixtures based on their chemical properties. It is widely used in fields like biochemistry, pharmaceuticals, and environmental analysis. By exploiting differences in the interaction of substances with a stationary phase and a mobile phase, chromatography enables precise purification and quantification of compounds. Whether you're working with complex biological samples or industrial chemicals, chromatography is essential for obtaining high-quality results. Browse our peer-reviewed product directory to find the best chromatography systems, compare products, read customer reviews, and get pricing directly from manufacturers.PittconPittcon is one of the largest conferences and exhibitions dedicated to laboratory science. It brings together professionals and innovators in analytical chemistry, physics, and biology, offering a platform to explore the latest scientific tools and technologies. From cutting-edge laboratory instruments to emerging research trends, Pittcon is a must-attend event for professionals in research and development.

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