Wyatt Technology introduces new-generation detector DAWN HELEOS II at Pittcon 2013

21 Mar 2013

Product news

Wyatt Technology is showcasing its DAWN® HELEOS® II Multi-Angle Light Scattering (MALS) Detector, at booth #2133, PittCon 2013, March 17 – March 21, 2013 Pennsylvania Convention Center, Philadelphia, PA.

This new generation detector can incorporate both MALS and WyattQELS™ (Quasi-Elastic Light Scattering) into a single unit in order to measure simultaneously molar mass, radii of gyration and hydrodynamic radii. Whether in-line with chromatographic separation for analysis of distributions, or in stop-flow mode for characterizing interactions, the new HELEOS II offers more than twice the laser power and 1.6 times the sensitivity of Wyatt’s highly successful DAWN HELEOS, making it the most sensitive on-line light scattering instrument in existence.

Wyatt’s DAWN HELEOS II is the only light scattering detector in the world capable of achieving a dynamic range of 126 dB, enabling the instrument to virtually never go off scale. This results in faster sample runs, offering a wider range of sample concentrations than ever previously attained. The instrument also utilizes a new 24 bit A/D measurement system, with separate A/Ds for each detector channel. This provides the same high sensitivity over the entire range of scattering intensities, rendering post-detector amplifiers unnecessary.

By utilizing the DAWN HELEOS II, the light scattering process is simplified, allowing the regulation of measurements to be completely automated. By incorporating an air cooled Peltier to temperature-regulate the sample, the process can operate at temperatures between -15ºC and 150ºC, thus achieving a stability that is greater than 0.01ºC. The ultra-high version operates from 30ºC to 210ºC. Furthermore, the HELEOS is able to operate on a corporate network due to its Ethernet interface, thus allowing the user to control or view the status of the instrument from multiple locations.
The HELEOS II can be incorporated seamlessly with all other Wyatt instruments, such as the ViscoStar® differential bridge viscometer, via its Ethernet interface. It has the capability of taking signals from a variety of third party instruments, such as UV absorption, DRI, IR absorption, evaporative light scattering or photodiode array detectors.

Wyatt Technology, the inventor of the world’s first commercial MALS instruments, has applied its 27 years of experience into the development and manufacturing of light scattering equipment to further demonstrate its commitment to the field of absolute macromolecular characterization. The DAWN HELEOS II represents a new generation of light scattering instrumentation, providing absolute measurements for results of the highest accuracy for use in the biotechnology, chemical, petrochemical and pharmaceutical industries.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Particle CharacterizationParticle characterization instruments are used to determine particle size distribution, shape, surface area, zeta potential, density and porosity of particles and materials. Multiple tecchniques are available for determining particle size, shape and count including dynamic light scattering (DLS), laser diffraction, electrozone (Coulter technique), imaging particle analysis and single particle optical sensing. Determine the density of your material with a gas pycnometer or examine its surface area and porosity with gas adsorption analyzers and mercury porosimeters. Find the best particle characterization instruments in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.PittconPittcon is one of the largest conferences and exhibitions dedicated to laboratory science. It brings together professionals and innovators in analytical chemistry, physics, and biology, offering a platform to explore the latest scientific tools and technologies. From cutting-edge laboratory instruments to emerging research trends, Pittcon is a must-attend event for professionals in research and development. Molecular Weight AnalysisMolecular weight analysis determines the size and structure of biomolecules, essential in protein characterization, polymer studies, and drug development. Techniques like mass spectrometry ensure precise results. Compare solutions for molecular weight analysis in our peer-reviewed product directory.
Wyatt Technology introduces new-generation detector DAWN HELEOS II at Pittcon 2013