Wren Laboratories announces discontinuation of NETest 1.0 in favor of advanced NETest 2.0

NETest 2.0, an AI-powered, non-invasive diagnostic tool, sets a new benchmark in NET detection and treatment monitoring with enhanced precision, global validation, and predictive capabilities for PRRT response

7 Mar 2025

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Wren Laboratories announces discontinuation of NETest 1.0 in favor of advanced NETest 2.0

Wren Laboratories, a leader in liquid biopsy diagnostics, confirms the official discontinuation of the original NETest 1.0, which has been replaced by the cutting-edge NETest 2.0. This next-generation test marks a significant advancement in precision medicine for neuroendocrine tumor (NET) diagnostics.

NETest 2.0 is an AI-enhanced, non-invasive liquid biopsy test that leverages a refined 51-gene mRNA expression algorithm to offer unmatched diagnostic and prognostic accuracy:

  • >95% sensitivity for detecting NETs
  • >90% accuracy in identifying progressive disease
  • PPQ Score – Predicts patient response to PRRT (98% PPV, 93% NPV)
  • Validated in patient cohorts across the U.S., Europe, Latin America, Africa, and Asia

“NETest 2.0 represents a major leap forward in patient surveillance and therapeutic decision-making for individuals with NETs,” said Dr. Abdel Halim, PharmD, PhD, CEO/CSO of Wren Laboratories. “By integrating advanced machine learning with extensive global validation, we’re setting a new standard for non-invasive tumor monitoring.”

“Clinicians need a reliable, data-driven tool to make informed treatment decisions,” added Dr. Mark Kidd, Laboratory Director at Wren Laboratories. “With NETest 2.0, we’ve significantly enhanced diagnostic precision, allowing for improved patient surveillance and better treatment outcomes.”

“NET patients, specifically being treated with radiopharmaceutical therapies and under active surveillance may profit from state-of-the-art biomarkers like NETest2.0,” shared by nuclear medicine expert and associate professor of radiology for Mallinckrodt Institute of Radiology at Washington University School of Medicine of St. Louis, Dr. Vikas Prasad, MD, PhD. “Integration of the 51-gene mRNA expression-based biomarker with imaging biomarker has the potential to further improve NET patients care.”

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Clinical GeneticsMolecular Genetics covers the analysis of hereditary genetic disease and chromosomal abnormalities. Genetics can be analysed using DNA, RNA, and protein microarrays, PCR, RT PCR and DNA sequencing. Genetic equipment includes genetic workstations, thermal cyclers, cooling blocks and electrophoresis products. Diagnostic kits are used for DNA / RNA extraction and purification.PathologyMolecularmRNAPrecision MedicinePrecision medicine refers to the idea of customized healthcare, where medical decisions and treatments are tailored to the individual patient. Molecular diagnostics, companion diagnostics and Next Generation Sequencing (NGS) play a pivotal role in this approach. Liquid BiopsiesLiquid biopsies are non-invasive tests used to detect cancer and other diseases by analyzing blood or other bodily fluids. This technique is gaining popularity for early detection, monitoring treatment response, and detecting minimal residual disease. Explore liquid biopsy solutions in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Patient CareDrug DevelopmentDrug development refers to the process of bringing a new drug to market.Neuroendocrine Tumors
Wren Laboratories announces release of Advanced NETest 2.0