Worthington Launches Animal Origin Free STEMzyme™ Collangenase/Neutral Protease Blends

9 May 2013
Sarah Thomas
Associate Editor

Product news

Worthington's new Animal Origin Free (AOF) STEMzyme™ Collagenase/Neutral Protease (Dispase®) Blends 1 and 2 are now available for primary and stem cell isolation, regenerative medicine, biopharma & cell bioprocessing applications.

STEMzyme™ 1 & 2 Collagenase/Neutral Protease (Dispase®) are specialized combinations of AOF Clostridium histolyticum Collagenase (Code: CLSAFB) and AOF Bacillus polymyxa Neutral Protease (Dispase®) with a minimum of 250 CLS units and 1,000 or 2,000 caseinase units per mg dry weight, respectively.

Produced at Worthington and designed for stem cell, regenerative medicine and other primary cell isolations and bioprocessing applications where introduction of potential animal derived pathogens must be prevented.

As an ISO9001 Certified primary manufacturer, Worthington can meet enzyme requirements from research-scale to bulk bioprocessing quantities.

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Cell Lines Stem Cells and Primary CellsPrimary cell cultures, established cell lines and stem cells are vital for <i>in vitro</i> and <i>ex vivo</i> experimentation. High-quality cells, optimized for your applications, alongside optimized cell substrates, growth medium and supplements, are critical for experimental success. Explore a range of cells suitable for your applications, including isogenic cell lines, competent cells, induced pluripotent stem cell (iPSC)-derived cell lines, fungal/bacterial/mammalian cell lines, stem cells and cancer cell lines. Find the best cells for your research in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Bioprocessing / FermentationBioprocessing is the use of biological materials to perform commercial, scientific or medical research processes. Biological materials used include cells, enzymes and organisms. Usually bioprocessing requires a batch or continuous bioreactor such as a fermentor or cell culture system. The advantages of using a reactor include high productivity, easy configuration, adjustable values and automation.ProteaseStem Cell ResearchStem cells have the ability to produce identical daughter cells as well as progeny, which commit and differentiate. Stem cell research has exciting prospects of biomedical applications in cellular disease modeling, pharmaceutical screening, and regenerative medicine. BiopharmaceuticalsBiopharmaceuticals are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or for in vivo diagnostics. The most well known example of a biopharmaceutical product, and the first to be approved for therapeutic use, was recombinant human insulin.Regenerative Medicine
Worthington Launches Animal Origin Free STEMzyme™ Collangenase/Neutral Protease Blends