Which UPLC System is Best for Your Application Needs?

Experts share tips on how to choose between quaternary and binary UPLC systems in our webinar later on Thursday, July 11

30 Jun 2019
Sarah Thomas
Associate Editor

Expert insights

An LC system, including the solvent delivery system or pump, is often chosen based on availability, history or personal preference. While many methods are not significantly impacted by the pump, some workflows or applications benefit from either of the two most commonly used LC pumps: binary and quaternary.

In our upcoming webinar, chromatography experts from Waters Corporation, Principal Consulting Scientist, Paula Hong, Ph.D., and Principal Scientist, Jennifer Simeone, will review how the binary and quaternary pumps deliver mobile phase to the column, along with the physical characteristics that impact separations, particularly for gradient methods.

The webinar will also cover key application areas that might benefit from either the binary or quaternary pump, including method development, automated pH adjustment of mobile phase, long shallow gradients, routine analysis and high-throughput gradient methods. This discussion will provide the listener with a better understanding of the physical pump characteristics and how these features might impact gradient separations.

You’ll also have the opportunity to ask our speakers any questions you might have on this topic during the dedicated question and answer session.

Register your place today.

Join us to learn:

  • The key differences between binary and quaternary pumps
  • Which applications may benefit from a particular pump
  • How to select an LC system based on your application needs


Want to attend, but have a scheduling conflict? Click here to register and receive an on-demand link to watch later.

All webinar participants can request a certificate of attendance, and a learning outcomes summary document for continuing education purposes - register now >>

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Chromatography Method DevelopmentChromatography method development is the process of designing and optimizing chromatographic techniques to separate and analyze complex mixtures. This includes selecting appropriate stationary and mobile phases, determining flow rates, and optimizing detection methods. Successful method development is essential for high-quality results in fields like pharmaceuticals, food safety, and environmental analysis. Explore chromatography method development tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.ChromatographyChromatography is a powerful technique used to separate and analyze components of mixtures based on their chemical properties. It is widely used in fields like biochemistry, pharmaceuticals, and environmental analysis. By exploiting differences in the interaction of substances with a stationary phase and a mobile phase, chromatography enables precise purification and quantification of compounds. Whether you're working with complex biological samples or industrial chemicals, chromatography is essential for obtaining high-quality results. Browse our peer-reviewed product directory to find the best chromatography systems, compare products, read customer reviews, and get pricing directly from manufacturers.
Which UPLC System is Best for Your Application Needs?