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Wheaton’s New AntiBIND™ Microplates Virtually Eliminate Non Specific Protein Binding, Increasing Sample Recovery and Improving the Accuracy of Test Results

WHEATON

Wheaton’s New AntiBIND™ Microplates Virtually Eliminate Non Specific Protein Binding, Increasing Sample Recovery and Improving the Accuracy of Test Results

26 Jan 2016
Alex Waite
Editorial Assistant

Product news

The new product line, to be launched at SLAS2016, is the only technology to modify at the molecular level the surface of polypropylene plates, significantly reducing protein surface binding and adsorption.

WHEATON® announces the launch of its new AntiBIND microplate product line that significantly reduces protein binding and adsorption, factors that until now could significantly hamper researchers working with rare proteins. The AntiBIND line of products employs a newly patented technology that changes the surface of polypropylene plates from hydrophobic to hydrophilic, resulting in protein recovery increases of as much as 100 percent compared with competitive low binding plates.

“Our new AntiBIND product line represents a significant breakthrough for protein researchers. By changing the surface of our polypropylene microliter plates from hydrophobic to hydrophilic, we provide superior performance that minimizes both protein adsorption and protein surface binding. Because the proteins are not bound you can be assured of accurate analytical results,” said Wayne Brinster, President and CEO of WHEATON®. “This product line builds on our 126-year history as an innovator of both glass and plastic products purpose built for the specific research needs of our customers.”

Two products in the new AntiBIND line will be launched at the Society for Laboratory Automation and Screening to be held January 23-27 in San Diego: The AntiBIND 0.5mL 96 Deepwell Microplate and the 230 µl 384 well microplate. Two additional products will be launched this spring: a 1.0mL 96 Deepwell microplate and a 2.0mL 96 Deepwell microplate, with additional AntiBIND products in development.

“These specialty microplates provide a significant advantage to our customers who know the difficulties presented by plastic surfaces when working with proteins,” said Brinster. “Surface coatings in the presence of organic solvents can dissolve, leaving researchers with both the problem of binding as well as having a foreign substance to interfere with their test.”

For more information about Wheaton visit their website here.

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MicroplatesMicroplates are multi-well plates used to increase the throughput of biological investigations. The number of wells microplates contain can range from 6 to 3243 wells, with the 96-well format being the most commonly used. Microplates can come tailored for a range of applications including cell culture, PCR, filtration, storage, non-binding surface, protein crystallization, as well as pre-coated, deep well and normal Standard microplates. Additionally, options for microplate colors include clear , black, white or black with clear bottom and white with clear bottom for absorbance microplate reader applications. Find the best microplates for your lab in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Protein CrystallographyProtein crystallization is the process of crystallizing purified proteins for 3D structure analysis by x-ray crystallography. The main methods of protein crystallization include sitting drop, hanging drop and microbatch. It is important to control parameters such as pH, temperature and concentration. Following crystallization, detectors and software are used for data collection and analysis.AutomationAutomation in laboratories and manufacturing processes enhances efficiency, precision, and scalability by reducing the need for manual intervention. It plays a critical role in improving productivity, minimizing human error, and accelerating workflows in fields like diagnostics, drug development, and industrial testing. Automation technologies include robotic systems, automated liquid handlers, and process control systems that streamline complex tasks and ensure consistent, reproducible results. Explore our peer-reviewed product directory to discover the best automation solutions, compare options, read user reviews, and get prices directly from manufacturers.Protein InteractionsProtein interactions are essential for understanding cellular processes, as proteins work together to carry out biological functions. Studying protein interactions can provide insights into disease mechanisms, drug development, and cell signaling pathways. Explore the best tools for protein interaction research in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.SLASThe Society for Laboratory Automation and Screening (SLAS) is an organization focused on laboratory automation, high-throughput screening, and biotechnology innovation. SLAS promotes scientific advancements through conferences, publications, and industry collaborations.

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Wheaton’s New AntiBIND™ Microplates Virtually Eliminate Non Specific Protein Binding, Increasing Sample Recovery and Improving the Accuracy of Test Results