Webinar Highlights, Parts One to Four: Technology Accelerating Biopharma: Complete Workflow Solutions in Biopharmaceutical Discovery and Development

Read highlights from all four sessions of this exciting webinar series

1 Feb 2016
Lois Manton-O'Byrne, PhD
Executive Editor

Expert insights

Protein biopharmaceuticals are being developed at an explosive rate and have attracted great interest from both smaller biotech firms and big pharma. But discovery and development of biopharmaceuticals is difficult. There are many challenges, and scientists must not only stay abreast of advances in knowledge and improvements in technology, but also navigate the maze of shifting government regulations. Making good decisions fast is critical.

In this two-day webinar events series, industry experts from Agilent Technologies discussed native protein characterization, LC/MS workflows and much more.

Part one: LC/MS Workflows for Biosimilars & Antibody Drug Conjugates and Solutions for the Core and Protein Laboratory: MassHunter Walkup

Read highlights of part one, or watch on-demand

Part two: Native Protein Characterization Using the Agilent 6560 Ion Mobility Q-TOF and Enhanced Software Tools for Biopharma Analysis

Read highlights of part two, or watch on-demand

Part three: Automated Sample Prep for Biopharmaceutical Analysis

Read highlights of part three, or watch on-demand

Part four: Identifying Released Glycans in a HILIC-FLR-MS Workflow Using Free Software Tools and Enabling Mass Measurement from Bioseparations: A HIC/RP Multiple Heart-cutting 2D- LC/MS Platform

Read highlights of part four, or watch on-demand

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Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. GlycobiologyGlycobiology encompasses research into the biological functions, synthesis and structures of glycans, including glycoproteins, glycolipids, proteoglycans and free oligosaccharides. Mass spectrometers and their software are commonly used in the study of glycobiology, along with structure predicting tools, chromatography and NMR.GlycansProtein BiologyThe analysis of protein expression, identity and function is vital for many areas of life science research and drug discovery. Some of the most commonly used techniques in protein analysis include Western blotting, electrophoresis and mass spectrometry.BiopharmaceuticalsBiopharmaceuticals are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or for in vivo diagnostics. The most well known example of a biopharmaceutical product, and the first to be approved for therapeutic use, was recombinant human insulin.Antibody Drug Conjugates