Webinar Highlights: Obtaining Ultimate Efficiency and Maximizing Selectivity with CORTECS Solid-Core Columns
10 Nov 2016
Expert insights
Solid-core columns can be used to maximize your laboratory throughput
Bonnie A. Alden Senior Research Scientist, Waters Corporation
In this webinar, Bonnie A. Alden, senior research scientist at Waters Corporation discussed how solid-core columns deliver increased efficiencies over fully-porous particles of a similar size. The webinar also details how you can select the best column for your work, and can maximize laboratory throughput using solid-core columns.
Read on for highlights from the Q&A session of the webinar, and if you missed it, watch the webinar on-demand.
Q: What are the pH limitations on the solid-core columns?
A: The limitations are pH 2-8, the same as any silica column. If you are using the column at elevated temperatures >45 deg C (recommended temp. max) lifetime will be decreased at elevated pH.
Q: Should I be concerned about operating at high pressures?
A: No – CORTECS Columns are based on a rugged solid-core particle, where the superficially porous shell is fused to the solid silica core. The 1.6 µm is designed to be run on UPLC systems which operate up to 15-18,000 psi. The 2.7 µm CORTECS is designed to operate on UHPLC/HPLC systems that have a pressure limit of ~10,000 psi.
Q: Can the 2.7 μm columns be used on HPLC systems?
A: Yes. 2.7 μm columns are the new standard in highly efficient HPLC columns, it will work fine on all standard HPLC systems.
Q: How much pressure do the 2.7 μm columns generate?
A: Hard to say, as the back pressure of the column depends on your mobile phase viscosity, temperature, flow rate, and which column dimension is being used. You also have to factor in the system pressure, for the complete pressure profile.
Miss the live webinar? Watch the full webinar on demand here.
Do you use any of the technology discussed in this webinar? Write a review today for a chance to win an Amazon voucher worth $400 (or equivalent currency) or an iPad Air®.
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CORTECS® Columns
WatersUnleash the power of your laboratory's instrumentation. CORTECS® 1.6 µm and 2.7 µm solid-core columns deliver new levels of performance. CORTECS Columns are available in both reversed-phase and HILIC options, giving you the flexibility and power to develop methods for challenging separations even faster. With different particle characteristics and innovative charged surface modifications, CORTECS Columns are suitable for use in a wide variety of applications. CORTECS Columns offer particle sizes ideal for HPLC, UHPLC, and UPLC platforms, assuring a simple, seamless method transfer with consistent results across different particle sizes and column configurations. CORTECS 1.6 µm and 2.7 µm solid-core columns are suitable for use in a wide variety of applications. CORTECS Columns offer particle sizes ideal for HPLC, UHPLC, and UPLC platforms, assuring a simple, seamless method transfer with consistent results across different particle sizes and column configurations.