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Waters Progenesis QI Marks Next Generation of LC-MS 'Omics Analysis at analytica

8 Apr 2014
Sarah Thomas
Associate Editor

Product news

Waters Corporation recently unveiled two new data analysis software packages for proteomics and metabolomics/lipidomics analyses: Progenesis® QI and Progenesis QI for Proteomics. These new releases of the highly acclaimed software packages are an early result of Waters' acquisition of Nonlinear Dynamics Ltd., the world leader in 'omics data analysis software.

Progenesis QI software enables researchers to accurately quantify and identify compounds and proteins with unique methods to analyze and visualize LC-MS data. Supporting all common LC-MS data formats and with intuitive guided workflows, Progenesis QI software allows customers to rapidly, objectively and reliably discover compounds and proteins of interest in their valuable samples.

“The development of Progenesis QI is a great example of the innovation outcome for ‘omics-focused scientists and laboratories that we at Waters envisioned when we combined Nonlinear Dynamics informatics expertise with Waters worldwide leadership in chromatography and mass spectrometry,” said Dr. Rohit Khanna, Vice President of Informatics and WW Marketing for the Waters Division. “With these latest releases, we have combined the functionality of legacy 'omics-based data analysis software packages into a pair of stronger, broader reaching offerings. Progenesis QI maintains the heritage of previous releases and focuses our resources in delivering a suite of focused, world-leading informatics packages for 'omics data analysis.”

In response to customer feedback, new features of Progenesis QI include fragment ion support for compound identification, automation of data processing workflows, and improvements in data import routines for enhanced signal differentiation over background noise. Furthermore, new abilities to utilize Waters' ion mobility data as well as MSE and HDMSE data independent analysis is a direct outcome of merging of Waters and Nonlinear Dynamics innovations.

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LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Chem / BioinformaticsCheminformatics and bioinformatics are computational techniques used in chemistry and biology, respectively, for data acquisition, processing and storage. Cheminformatics focuses on compound information, whereas bioinformatics is mainly applied to analysis and modeling of genomics, genetic and sequencing information. Hardware and software is available for data acquisition, analysis, management and storage.MetabolomicsMetabolomics is the study of small metabolites (the intermediates and products of metabolism). It involves the identification and quantification of cellular metabolites using analytical technologies such as GC, HPLC, NMR, and LC/MS.Protein BiologyThe analysis of protein expression, identity and function is vital for many areas of life science research and drug discovery. Some of the most commonly used techniques in protein analysis include Western blotting, electrophoresis and mass spectrometry.analyticaAnalytica is a leading international trade fair for laboratory technology, analysis, and biotechnology, showcasing innovations and solutions in the scientific community. Stay updated with the latest trends and products in the industry. LipidsLipids are a diverse group of organic compounds that are insoluble in water, including fats, oils, and hormones. They are critical for cellular structure and energy storage. Explore lipid analysis tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.

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Waters Progenesis QI Marks Next Generation of LC-MS 'Omics Analysis at analytica