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Waters Introduces nanoEase M/Z Columns

Waters

Next-generation columns are easy to install and reduce chromatographic variability during proteomics and biomarker research

11 Jun 2017
Weylan Kiam-Laine
Microbiologist

Product news

Waters Corporation has introduced the next generation columns for nano- and microflow UPLC/MS applications. The Waters® nanoEase™ M/Z columns are simple to install, reduce connection variability and deliver superior chromatographic performance.

nanoEase M/Z columns utilize ZenFit™ Connection Technology to significantly streamline the installation of columns and traps. This reduces chromatographic inconsistencies caused by variations in the connections. ZenFit Connectors are easy-to-use, finger tight, require no tools, and include re-useable fittings for critical fluid connections in nano- and micro-flow UPLC/MS.

In addition to being easier than ever to install, the state-of-the-art nanoEase M/Z columns deliver the high efficiency and selectivity expected from Waters. The columns are packed with sub-2-particles suitable for complex proteomics and biomarker discovery applications.

nanoEase M/Z columns are specifically tested for protein and peptide analysis and are available in several pore sizes and with several bonded phases including BEH C18, CSH C18, HSS T3 or Symmetry C18 (trap column only).

Shipping in mid-June, the nanoEase M/Z columns will greatly simplify the user experience for Waters nanoLC customers utilizing the Waters ACQUITY® UPLC® MClass System, while also bringing the benefits of the Waters nano- and micro-scale columns to users of third-party nanoLC/MS systems.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :PeptidesPeptides are short chains of amino acids that play key roles in biological processes, including signaling, immune responses, and enzyme regulation. Peptide research is critical in drug discovery, diagnostics, and vaccine development. Browse our peer-reviewed product directory to find the best peptides and peptide-related products, compare options, check reviews, and get pricing directly from manufacturers.Biomarker DiscoveryClinical biomarkers refer to substances related to known medical conditions that can be accurately measured <i>in vitro</i>. Biomarkers can be used to diagnose presence of a disease and indicate disease severity. The discovery of new biomarkers is incredibly valuable in the field of diagnostics.

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Waters Introduces nanoEase M/Z Columns