Waters Introduce the New Prep 150 LC System for Medicinal Chemistry and Natural Product Extraction at Pittcon 2013

18 Mar 2013
Sarah Thomas
Associate Editor

Product news

Waters Corporation introduced today the Waters® Prep 150 LC System, a new fit-for-purpose preparative chromatography system designed to isolate target compounds from crude mixtures synthesized in the laboratory or extracted from natural sources during initial purification processes.

“With this system we are responding to requests from scientists for a robust, reliable and dedicated personal chromatography system that can manage the occasional or everyday purification needs of scientists at the bench,” said Wendy Harrop, Product Manager, Waters Division. “The introduction of this system demonstrates Waters commitment to serve the needs of scientists not only for analytical-scale LC but for preparative-scale purification as well.”

Based on innovative high performance liquid chromatography (HPLC) hardware and software, the Waters Prep 150 LC System features ChromScope™ software intended for scientists and technicians of all skill levels - from novice to expert - with minimal training. This dedicated HPLC system enables chemists to purify and capture quantities of specific molecular entities as part of their research into new drugs, natural products, and specialty chemicals.

The Waters Prep 150 LC System operates at flow rate ranges of up to 150 mL/min. and features options for detection, sample injection, and solvent delivery systems in order to better suit specific application needs. The Prep 150 LC is supported with a full complement of scalable Waters OBD™ preparative 10 - 50 mm (i.d) columns featuring 5 - 10 micron chemistries.

Waters anticipates shipping the first production units during the 2nd quarter of 2013.

Prep 150 LC System

Waters

The Prep 150 LC System is a fit for purpose solution designed for scientists requiring robust system performance with intuitive software for dedicated personal purification or quick adoption in centralized labs. Systems are designed to satisfy your application requirements, whether you are processing a few samples a day, or your workload demands greater through-put with unattended automation. The Prep 150 LC System allows you to rapidly process your valuable complex mixtures resulting in high-purity and recovery with complete confidence. Features of the Prep 150 LC System: Flexible solvent delivery options allowing binary or quaternary based pumps providing low-pressure multi-solvent blending or high pressure gradient mixing of flow rates up to 150 ml/min. Easy to use manual or automated sample injection options allow the versatility to accommodate a wide range of workload requirements. Identify and isolate your compounds of interest with the highly sensitive 2489 UV/Visible or 2998 Photodiode Array detectors, providing enhanced linear range to accommodate highly concentrated samples. Confidently purify sample loads of milligrams to grams when using internal column diameters of up to 50mm. Use the easy-to-navigate ChromScope software delivered with sample set wizard, stacked injection wizard, key fraction collection parameters, fraction simulation modeling, and customizable reporting with drop and drag features.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.HPLC Method DevelopmentIt is important to develop and validate HPLC methods in order to identify, quantify or purify compounds of interest in the most efficient way. Effective method development ensures optimization, quality control and cost effectiveness.PittconPittcon is one of the largest conferences and exhibitions dedicated to laboratory science. It brings together professionals and innovators in analytical chemistry, physics, and biology, offering a platform to explore the latest scientific tools and technologies. From cutting-edge laboratory instruments to emerging research trends, Pittcon is a must-attend event for professionals in research and development.