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Waters Improves and Extends Tandem Quadrupole MS Portfolio with Upgraded Xevo TQ-S Micro and New Xevo TQ-S Cronos

Waters

Designed for quantitative analysis, Waters' full portfolio of TQ MS systems makes high performance and routine analysis accessible, robust, reliable

30 Jul 2019
Georgina Wynne Hughes
Editorial Assistant

Product news

Waters Corporation has reinforced its tandem quadrupole mass spectrometry portfolio with upgrades to the Xevo™ TQ-S micro and the introduction of the new Xevo TQ-S cronos.

The highly-acclaimed Xevo TQ-S micro features new performance enhancements that bring the quantitation of highly polar, ionic compounds in food to a higher level. The Xevo TQ-S cronos is a new, tandem quadrupole mass spectrometer purposely-built for routine quantitation of large numbers of small-molecule organic compounds over a wide concentration range. The upgraded Xevo TQ-S micro and the new Xevo TQ-S cronos complement the sensitivity of the Waters high performance Xevo TQ-XS. They are also well suited to meet regulatory requirements for pesticide residue analysis, the monitoring for contaminants in processed foods, identifying drugs of abuse, and performing impurity profiling of pharmaceuticals. The updates to the Xevo TQ-S micro are inclusive of all systems, including in vitro diagnostic medical devices.

“Today’s quantitative laboratories are under pressure to increase sample throughput and reduce turnaround times, quantify more analytes per sample, and contend with more complex sample matrices,” said Mike Wilson, Director, Mass Spectrometry Product Marketing. “Today’s introduction of the compact, versatile Xevo TQ-S micro and Xevo TQ-S cronos systems combined with the highly sensitive Xevo TQ-XS system ensure Waters’ tandem quadrupole MS portfolio can meet any customer’s quantitation needs across the board.”

Both the upgraded TQ-S micro and new Xevo TQ-S cronos come with many of the signature features synonymous with the popular Xevo product line including the StepWave™ ion guide for long-lasting sensitivity and performance, tool-free probe maintenance and ionization source cleaning, a choice of ionization sources including UniSpray™ for analyzing a broader range of compounds with greater ionization efficiency, automated start up and system optimization provided by IntelliStart™, simplified method development and transfer with Quanpedia™ and streamlined data review and processing with TargetLynx™ XS Software.

The Xevo TQ-S micro and Xevo TQ-S cronos are currently available for customer shipments worldwide.

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The TargetLynx™ Application Manager automates sample data acquisition, processing and reporting for quantitative results.It incorporates a range of confirmatory checks that identify samples that fall outside user-specified or regulatory thresholds. Identify Non-compliant Samples TargetLynx rapidly identifies and flags samples where: Analytes are above a specified maximum reporting level (MRL) Analyte confirmatory ion ratios are outside specified limits One or more analyte signal-to-noise ratios are below a defined value An analyte retention time or relative retention time is outside limits An analyte concentration is below set LOD and LOQ thresholds The standard deviation of response for QC standards exceeds a defined value The blank response is too high The coefficient of determination (r2) of the calibration curve exceeds a defined value LC/MS & LC/MS/MS and GC/MS & GC/MS/MS Use TargetLynx to quantify and confirm both LC/MS & LC/MS/MS and GC/MS & GC/MS/MS data. This data may be selected ion monitoring (SIM), multiple reaction monitoring (MRM), or full scan/full spectrum. In the case of full scan/spectrum data, extracted ion chromatograms are used for quantification. Ensure Regulatory Compliance The demand by regulatory authorities for assurance of confirmation in quantitative analysis continues to increase. To ensure cost-effective compliance, TargetLynx offers software that gives you confidence in your results and eliminates time-consuming, costly manual checks.

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. Software PlatformsSoftware platforms are useful for various stages of laboratory experiments from data collection to data storage and processing. For instance lab software is available for system control, data management, data analysis and qualification / validation.PesticidesPesticides are used to protect crops from diseases, pests and unwanted plants. They are classed as persistent organic pollutants (POPs) and can be harmful to humans. The Environmental Protection Agency (EPA) currently regulates the use of pesticides in the USA. Drugs of AbuseA drug of abuse is a drug that has been taken for non-medical purposes. Such drugs can have mind-altering effects, with some causing dependence and addiction.Food ContaminationFood contamination refers to the presence of harmful substances or pathogens in food, posing risks to human health. Contaminants can be biological, chemical, or physical, and their detection is crucial for ensuring food safety. Advanced testing methods like PCR, chromatography, and spectroscopy are used to identify contaminants in food products. Browse our peer-reviewed product directory to find the best solutions for food contamination detection, compare products, check reviews, and get pricing directly from manufacturers.PharmaceuticalsPharmaceuticals are medicinal drugs used in healthcare to diagnose, prevent, cure and treat illnesses. Pharmaceuticals that are excreted after use appear in wastewater and can have detrimental effects on the environment.LC-MSLiquid Chromatography-Mass Spectrometry (LCMS) is a powerful analytical technique that combines the separation power of liquid chromatography with the detection capabilities of mass spectrometry. It is widely used for qualitative and quantitative analysis of complex mixtures in pharmaceuticals, proteomics, and environmental studies. Browse our peer-reviewed product directory to find the best LCMS systems, compare products, check reviews, and get pricing directly from manufacturers.

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