Waters Corporation and Thermo Electron Agree to Integrate Ultra Performance Liquid Chromatography with Mass Spectrometry Products

8 Mar 2006

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Waters Corporation (NYSE: WAT) and Thermo Electron Corporation (NYSE: TMO) have entered into a collaborative agreement to provide greater integration and connectivity between the Waters® ACQUITY Ultra Performance LC™ (UPLC™) system and Thermo’s full range of innovative mass spectrometers (MS).

These instruments include Thermo’s Finnigan™ TSQ Quantum™, LTQ™ Linear Ion Trap, LTQ FT™ Hybrid Linear Trap/Fourier Transform ICR and LTQ Orbitrap™ hybrid mass spectrometer.

The collaboration is in response to scientists and laboratory technicians in the mass spectrometry community who seek the advantages in certain applications of using UPLC with MS, which includes increased throughput and performance. These same users also want more unified control and results management software to seamlessly combine these complementary technologies.

“UPLC peaks are narrower and sharper, signal-to-noise ratios are higher, and run times are shorter – which are all key factors in enhancing the performance of virtually any mass spectrometer thus bringing laboratories new levels of efficiency. For Waters customers, the seamless combination of UPLC technology with Thermo’s high performance mass spectrometry systems promises to bring laboratories more information per unit of time resulting in greater productivity," said Rohit Khanna, Vice President of Worldwide Marketing, Waters Corporation.

Iain Mylchreest, VP and General Manager of Life Sciences Mass Spectrometry for Thermo adds, “This collaboration continues Thermo’s commitment to provide its customers with advanced technology options to improve overall system performance. Since mass spectrometers comprise one of Thermo’s largest and fastest growing product lines, and customers have seen the benefits of UPLC technology in combination with Thermo’s high performance mass spectrometry systems, it makes sense to give customers this front-end choice.”

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer.