Waters Corporation and Bruker BioSciences Announce Collaboration Collaboration to Integrate ACQUITY UPLC System With Bruker MS Products

9 Mar 2006

Product news

Waters Corporation (NYSE: WAT) and Bruker BioSciences Corporation (NASDAQ:BRKR), Billerica, MA, have entered into a collaboration agreement to provide greater integration and connectivity between Waters® ACQUITY Ultra Performance LC™ (UPLC™) system and Bruker's mass spectrometry (MS) and nuclear magnetic resonance (NMR) products.

The collaboration will allow direct support of Waters ACQUITY UPLC System in Bruker’s HyStar™ software thus unifying control and results management to seamlessly combine these complementary technologies. The products of both companies play an important role in the discovery, development, and manufacture of pharmaceuticals, processed foods, beverages, personal care products, and in environmental and food safety laboratories.

"Scientists are always looking for a competitive edge and many have experienced the advantages of using UPLC with MS," said Rohit Khanna, Ph.D., Vice President – Worldwide Marketing, Waters Corporation. "Combining UPLC with mass spectrometry brings scientists measurable improvements in performance and in the overall quality of information they obtain from their LC/MS and LC/NMR analyses resulting in improved decision-making, increased productivity and reduced business risk."

UPLC and MS – A Natural Fit

Mass spectrometry results are highly-dependent on the liquid chromatography separation preceding ionization and confirmatory analysis in the mass spectrometer.

Compared to conventional high performance liquid chromatography (HPLC), UPLC results are significantly better – peaks are narrower and sharper, signal-to-noise ratios are higher, peak capacity is greater, run times are shorter – which are all key factors in reducing the effects of ion suppression and enhancing the performance of virtually any mass spectrometer, thus bringing laboratories new levels of efficiency. For Waters and Bruker customers, the seamless combination of UPLC technology with mass spectrometry promises to bring their laboratories more information per unit of time resulting in greater productivity.

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LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer.