Waters Continues Its 20-Year Commitment with Enhancements to Mass Spectrometry Detection for Chromatographers

New Release Adds Improved Mass Data Quality and Peak Tracking Capabilities

9 Mar 2016
Alex Waite
Editorial Assistant

Product news

Waters Corporation announced the latest feature release of Empower® 3 chromatography data software.

Expanding on its 20 years of mass spectrometry (MS) data acquisition and processing, Empower 3 Feature Release 3 (FR3) adds peak tracking by assigned mass to the long list of Empower software features. The use of mass data in combination with UV data allows the analyst to more accurately identify peaks, but retains the more familiar look of UV chromatograms.

Instrument method conditions change as part of the method development process; as a result, the individual peaks can move and change position. The use of the peak tracking tool in Empower 3 (FR3) software will enable the analyst to identify each peak by its mass and allow them to track each peak from one injection to the next.

"As more laboratories take advantage of the power and accessibility of new mass detectors like the ACQUITY® QDa® detector, this exposes the need for chromatographer-friendly interfaces that deliver the additional information in a way that is easy to build into their workflow – mass assignment and peak tracking capabilities within the Empower Report Publisher are enhanced in Empower 3 FR3, further opening the door to better decisions and generating immediate value for chromatographers," said Andy Craze, Senior Director, Informatics Marketing & Business Development.

In addition, Empower 3 FR3 allows for improved harmonization of business processes. More and more companies are recognizing the benefits of Empower Enterprise software and consolidating their personal Empower software installations, or smaller lab wide or site wide Empower Enterprise software, into large enterprise installations that provide Empower software access across different cities, countries and continents. This latest release adds the ability to assign 'location' to users, instruments and workstations, enabling better asset utilization assessment and traceability for system administrators and business managers.

"The drives for improved data integrity and business productivity are both key factors we focused on for the latest release of our Empower software," Craze added.

ACQUITY QDa Mass Detector

Waters

The ACQUITY QDa® Mass Detector gives you certainty above all else. You can minimize the risk of unexpected coelutions or components and confirms trace components with the analytical confidence of mass detection. The ACQUITY QDa® Detector is a mass detector built around the needs of analytical scientists for chromatographic analysis. Robust, reliable and requiring no sample adjustments, it just integrates with your current LC, ACQUITY UPLC, ACQUITY UPC2 and purification systems. You'll enhance the analytical value and productivity of each analysis, and you won't need to run all the additional assays or time-consuming alternative techniques or even wait for results from specialist labs that cost your laboratory productivity. With the ACQUITY QDa® Detector, you now have information-rich mass spectral data to complement data from your current Waters® optical detectors, including the ACQUITY UPLC PDA, TUV, ELS, and FLR detectors, as well as the ACQUITY UPC² PDA Detector. This mass spectral information integrates seamlessly into the same workflow; routinely giving you more complete separation characterization. Features: Intuitive operation More information from every sample Effortless integration Increased efficiency Resolving complexity Applications: Food & Environment Life Sciences and Pharmaceuticals Chemical

(20)

Empower 3 Method Validation Manager (MVM)

Waters

Empower™ 3 Method Validation Manager (MVM), an option for Empower 3 Chromatography Software, allows you to perform chromatographic method validation, from protocol planning through final reporting, in one application.With Empower 3 MVM you can automatically: Manage method validation workflow in one comprehensive, automated application Clearly display the status of ongoing validation studies – enabling you to see at what step each individual validation parameter is in the method validation process Perform all result and statistical calculations in Empower 3, eliminating time-consuming data transfer to spreadsheets and the associated problems of transcription errors and security concerns Perform multi-component analyses and batch processing of method validation results Generate reports with standardized templates Empower 3 MVM provides a number of benefits to both the laboratory and organization, including: Cut method validation time and costs as much as 80% by eliminating manual steps in your current method validation process. Satisfy compliance requirements more easily while significantly improving data traceability. Eliminate the use of separate software applications during method validation. Automate, streamline, and simplify the method validation workflow. Easily determine if your data adheres to your method validation requirements and that your results are within specification. Store your method validation data securely and in one database.

(3)

Empower™ Chromatography Data System

Waters

The Empower Chromatography Data System is Waters’ compliance-ready chromatography data software (CDS) for advanced data acquisition, processing, and reporting that simplifies the management of chromatography test results.

(25)

Links

Tags

Gas ChromatographyGas chromatography (GC) is an analytical technique used to separate and quantitate mixtures of small and volatile compounds. Gas chromatographs or GC systems include components such as GC columns, detectors, pumps and autosamplers. Choose from packed or capillary GC columns, flame ionization (FID), photoionization (PID) electron capture detectors and selective or non-selective detectors. Find the best gas chromatographs in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Chem / BioinformaticsCheminformatics and bioinformatics are computational techniques used in chemistry and biology, respectively, for data acquisition, processing and storage. Cheminformatics focuses on compound information, whereas bioinformatics is mainly applied to analysis and modeling of genomics, genetic and sequencing information. Hardware and software is available for data acquisition, analysis, management and storage.Molecular Recognition SoftwareMolecular recognition software is widely used to analyze DNA, RNA, proteins and chemicals. The software can be useful for graphical viewing, comparative analyses, high-throughput screening, genomics, proteomics and phylogenetics. Molecular recognition software uses bioinformatics tools and analyses such as BLAST searches and generates structural predictions, 3D structures and sequencing information.Software PlatformsSoftware platforms are useful for various stages of laboratory experiments from data collection to data storage and processing. For instance lab software is available for system control, data management, data analysis and qualification / validation.Particle CharacterizationParticle characterization instruments are used to determine particle size distribution, shape, surface area, zeta potential, density and porosity of particles and materials. Multiple tecchniques are available for determining particle size, shape and count including dynamic light scattering (DLS), laser diffraction, electrozone (Coulter technique), imaging particle analysis and single particle optical sensing. Determine the density of your material with a gas pycnometer or examine its surface area and porosity with gas adsorption analyzers and mercury porosimeters. Find the best particle characterization instruments in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.GC-MS GC-MS (gas chromatography-mass spectrometry) instruments and equipment are used to separate, quantify and identify mixtures of small and volatile compounds, such as polycyclic aromatics, fatty acids and alcohols. Often used in drug detection, forensic investigation and environmental analysis for pesticides and contaminants, GC-MS is a powerful addition to your lab’s analytical capabilities. GC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzers can give greater sensitivity and resolution to your analysis. Find the best GC-MS instruments and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Method DevelopmentMethod development is the process of creating and optimizing experimental techniques and protocols to achieve reliable, reproducible results. This is essential in various fields, including pharmaceuticals, environmental science, and diagnostics. Browse our peer-reviewed product directory to find the best method development solutions, compare products, check reviews, and get pricing directly from manufacturers.Data AnalysisThe analysis of data is the process of transforming, modeling and evaluating data to discover useful information from experimental results. ChromatographyChromatography is a powerful technique used to separate and analyze components of mixtures based on their chemical properties. It is widely used in fields like biochemistry, pharmaceuticals, and environmental analysis. By exploiting differences in the interaction of substances with a stationary phase and a mobile phase, chromatography enables precise purification and quantification of compounds. Whether you're working with complex biological samples or industrial chemicals, chromatography is essential for obtaining high-quality results. Browse our peer-reviewed product directory to find the best chromatography systems, compare products, read customer reviews, and get pricing directly from manufacturers.Data Management