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Versatile multi-detector GPC/SEC system

Testa Analytical Solutions
27 Apr 2021
Ellen Simms
Product and Reviews Editor

Product news

The new HK Series Multi Detector GPC/SEC System, from TESTA Analytical Solutions e.K., combines high-performance chromatographic detector technologies and powerful, yet easy-to-use software to help unlock the secrets of even the most complex synthetic polymers and natural macromolecules.

Gel Permeation Chromatography / Size Exclusion Chromatography (GPC/SEC) is widely accepted as the analytical technique of choice to characterize polymers and separate mixtures into fractions including polymer, oligomer, monomer and any non-polymeric additives. GPC/SEC is also the 'go-to' technique for characterizing the molecular weight distribution of polymers.

However, increasingly widespread use of more complex synthetic polymers and macromolecules of natural origin such as proteins and peptides, requires advanced characterization technologies to allow researcher gain a thorough understanding of their shape, structure and related physical properties. GPC/SEC systems combining measurements from multiple detectors not only provides increased amounts of data, but also information, which is available due to the combination of different detectors that would not be obtainable using the individual detectors separately.

With the new HK Series Multi-Detector GPC/SEC System, you can choose from a wide combination of detectors including differential refractive index (DRI), Multiple Angle Light Scattering (MALS), viscometry, ultraviolet (UV) and flow measurement.

This versatile system can be used to analyze a wide range of polymers, regardless of molecular weight range or solvent. The combination of these different sensitive detectors can deliver accurate, absolute molecular weight, size and distribution information as well as useful data to derive fundamental parameters such as radius of gyration, concentration, intrinsic viscosity, specific refractive index increment (dn/dc) and second virial coefficient.

Each detector has independent temperature control to ensure that high levels of precision and reproducibility can easily be achieved from one day to the next. This powerful multi-detector GPC/SEC platform is supported by a powerful software suite that combines highly intuitive operation with all the necessary tools to generate and present results from the collected raw data.

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Size Exclusion ChromatographySize exclusion chromatography (SEC) is a liquid chromatographic technique used to separate and identify molecules based on their size, including polymers, proteins, nanoparticles & nucleic acid. SEC is further subdivided into gel filtration chromatography (GFC) and gel permeation chromatography (GPC) when an aqueous or organic mobile phase is used respectively. HPLC-based SEC systems and columns are available for analytical separation alongside SEC spin columns or filters to prep samples for many protocols. Find the best size exclusion chromatography equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Particle CharacterizationParticle characterization instruments are used to determine particle size distribution, shape, surface area, zeta potential, density and porosity of particles and materials. Multiple tecchniques are available for determining particle size, shape and count including dynamic light scattering (DLS), laser diffraction, electrozone (Coulter technique), imaging particle analysis and single particle optical sensing. Determine the density of your material with a gas pycnometer or examine its surface area and porosity with gas adsorption analyzers and mercury porosimeters. Find the best particle characterization instruments in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.PolymersPolymers are large molecules made up of many repeat units. Natural polymers such as DNA and proteins are essential to life, whereas synthetic polymers such as polystyrene and polyethylene are used widely due to their functionality. Typical techniques for analysis include GPC, SEC, DSC, FT-IR and NMR.SECSize exclusion chromatography (SEC) separates molecules based on size, ideal for protein purification, polymer analysis, and biopharma applications. SEC ensures precise characterization of biomolecules for research and industry. Explore peer-reviewed SEC products and compare options for your lab.

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Versatile multi-detector GPC/SEC system