Verogen partners with Cellmark Forensic Services to launch UK’s first ISO17025 accredited forensic next-generation sequencing service

The collaboration aims to enable the resolution of challenging forensic investigations and complex relationship cases

24 Oct 2021
Dora Wells
Clinical Content Editor

Industry news

Verogen Inc., a dedicated developer of human identification products for sequencing and analysis of forensic genomic samples, has announced a partnership with Cellmark Forensic Services. Cellmark is a leading provider of forensic DNA services in the United Kingdom and is the first forensic laboratory to receive ISO17025 accreditation from the United Kingdom Accreditation Service (UKAS) for next-generation sequencing (NGS), also known as massively parallel sequencing (MPS), for forensic DNA analysis. This accreditation enables Cellmark to offer NGS-based forensic services to its law enforcement partners, in keeping with the stringent quality standards required of forensic laboratories.

Verogen’s powerful new sequencing technology will supplement Cellmark’s existing specialist DNA capabilities. Verogen’s ForenSeq DNA Signature Prep Kit targets the core autosomal and Y-STR loci accepted by global databases, ensuring compatibility with existing DNA data. It also includes markers that provide advanced forensic intelligence such as hair color, eye color, and biogeographical estimations, all of which can be simultaneously interrogated using the versatile Verogen MiSeq FGx Sequencing System. The combination of sequence information and large number of forensically relevant markers will provide access to additional insight from low-quality, degraded and mixed samples, and enable the resolution of challenging forensic investigations and complex relationship cases.

“NGS is a huge leap forward in forensic DNA technology, and this accreditation demonstrates that it meets the rigorous standards necessary for introduction into forensic laboratories,” said Verogen CEO Brett Williams. “This partnership with Cellmark, through their implementation of the MiSeq FGx System, the ForesnSeq DNA Signature Prep Kit, and the Universal Analysis Software means Verogen’s tools will help bring closure to families looking for answers,” Williams added.

In 2019, Cellmark committed to becoming a UK center of excellence for sequencing-based forensic DNA profiling analysis. This accreditation follows Cellmark’s extensive technology validation and consultation with the UK’s Forensic Science Regulator, the Forensic Information Database Service (FINDS), UKAS, the Biometrics and Forensics Ethics Group, representatives from multiple police forces, and a close partnership with Verogen, to bring the benefits of forensic NGS technology to criminal investigations.

“UKAS is the sole national accreditation body recognized by the British government for accrediting forensic science laboratories to international quality standards,” said David Hartshorne, Managing Director of Cellmark Forensic Services. “Cellmark has a long history of forensic innovation. This accreditation and our close partnership with Verogen, the world’s leading forensic MPS technology provider, will allow us to deliver far greater forensic information than has previously been possible.”

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.DNA SequencingDNA sequencing, such as sanger sequencing, is a biological technique that determines the precise order of nucleotide bases in a fragment or template of DNA. DNA sequencers and genetic analyzers are based on capillary electrophoresis, where labeled DNA fragments are electrophoretically separated by size as they migrate through a polymer. Find the best DNA sequencing products, including DNA sequencing kits, genomic libraries and genetic identity kits in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Next Generation SequencingNext-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DNADeoxyribonucleic Acid (DNA) is the main component of chromosomes and the carrier of genetic information of living organisms. Find out here about PCR, NGS, ChIP-Seq, gel imaging, and many other techniques which can be used for the analysis of DNA.SequencingSequencing refers to determining the order of nucleotides in a DNA or RNA molecule. This process is essential in genomics, diagnostics, and evolutionary biology. Techniques like next-generation sequencing (NGS) and Sanger sequencing provide high-throughput and precise data for analyzing genomes and transcriptomes. Browse our peer-reviewed product directory to find the best sequencing tools and reagents, compare products, check reviews, and get pricing directly from manufacturers.Genome SequencingGenome sequencing involves determining the complete DNA sequence of an organism's genome. It provides crucial information about genetic variations, mutations, and diseases. Advances in sequencing technologies, such as next-generation sequencing (NGS), have accelerated research in genomics, diagnostics, and personalized medicine. Explore genome sequencing tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Forensic InvestigationForensic investigation is a diverse collection of scientific techniques and methods for the identification and characterization of chemicals relating to crime scene investigations.
Verogen partners with Cellmark Forensic Services to launch UK’s first ISO17025 accredited forensic next-generation sequencing service