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Validated Antibodies for Mammalian Epigenetic Research

Chromatrap

Chromatrap® announces that seven further popular antibodies have been validated for use in chromatin immunoprecipitation (ChIP) assays by their UK-based research team

8 Feb 2017
Weylan Kiam-Laine
Microbiologist

Product news

The new crop of antibodies represents some of the most frequently-cited antibodies in mammalian epigenetic research including H3K4me1, H4K5ac, H4K12ac, H2Az, H3, H4, H3K9me1 and H3K9me2.

In addition, the new ChIP validated antibodies are now available from Chromatrap® with matching primers. Purchasing Chromatrap® ChIP-validated antibodies with their matching high-quality primers, saves you time and gives you the confidence of using primers tested with the exact antibody and gene target with which you work.

All of these new products are available from the Chromatrap® UK facility by 1- or 2- day cold chain delivery. For further information please visit www.chromatrap.com or request a data sheet / pricing from support@chromatrap.com / +44-1978-666222.

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.Gene Expression and Molecular CloningMolecular cloning is a set of techniques that utilizes vectors to transfer recombinant DNA into host cells and is an essential tool for investigating the expression of genes and proteins in bacterial or mammalian cells. A variety of vectors optimized for gene cloning and expression in a range of host organisms are available, alongside competent cells for genetic replication. Here, you can explore a range of molecular tools, high-quality genomic and cDNA libraries, premade clones, transformation and transfection reagents and mutagenesis or gene expression detection assays and expression arrays. Find the best gene expression and molecular cloning products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Epigenetic AnalysisEpigenetic analysis products are used to study heritable phenotype changes that do not alter the DNA sequence, such as DNA modifications affecting gene activity. Determine whether genes have been methylated with DNA methylation quantification kits or methylation microarrays. Assess epigenetic regulation with histone modification kits or ChIP-on-chip microarrays. Kits are also available for bisulfite conversion and amplification of your samples, as well as epigenomic library preparation kits for next-generation sequencing (NGS). Find the best epigenetic products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Monoclonal AntibodiesMonoclonal antibodies (mAbs) are lab-made molecules that can bind to specific antigens on cells, making them highly effective in treating cancers, autoimmune diseases, and infections. These targeted therapies are transforming the treatment landscape for many conditions. Browse our peer-reviewed product directory to find monoclonal antibodies for research and clinical applications; compare products, check reviews, and get pricing directly from manufacturers.ImmunoprecipitationChIP-Sequencing

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Validated Antibodies for Mammalian Epigenetic Research