UV-clear microplates for DNA purity checking

Azenta Life Sciences presents Ultra Optically Clear assay plates, for DNA purity measurements

23 Feb 2024
Will Thompson
Editorial Assistant

Product news

Azenta_uac_image_2024
Ultra Optically Clear assay plates from Azenta Life Sciences

Ultra Optically Clear assay plates from Azenta Life Sciences provide high optical transmission in the UV waveband, which will benefit labs tasked with DNA purity measurements performed at 260/280 nm. The high UV waveband transmission of these plates is derived from an ultra-clear cyclic olefin copolymer (COC) base, which gives results by delivering low background absorbance and low autofluorescence.

Using a proprietary laser welding technique to attach a thin 70 um COC base to an opaque frame, the optical clarity of the plates combined with their low background noise delivers high transmission of signals at low UV wavelengths compared to standard optically clear bases made from glass or polystyrene. The optical performance provided by Azenta Ultra Optically Clear assay plates allows for the undertaking of DNA purity measurements in the plate well, without removing any sample, thus reducing sample loss, and improving throughput in automated workflows.

Manufactured from COC, Azenta Ultra Optically Clear assay plates are not only more robust than quartz-based assay plates, but also offer excellent chemical resistance to a wide range of solvents including dimethylsulfoxide (DMSO), ketones and alcohols which are known to degrade standard polystyrene plates.

To safeguard their optical surface from scratches and ensure consistently clear results, each plate comes with a protective film. Additionally, the assay plates are free from DNase, RNase, and human genomic DNA.

Each Ultra Optically Clear assay plate features an alphanumeric grid enabling well and sample identification. If required, the plates can be supplied with a low-profile lid to help preserve sample integrity or barcoded to help streamline automation.

Want the latest science news straight to your inbox? Become a SelectScience member for free today>>

Links

Tags

Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Labware and Lab SuppliesLabware and lab supplies include various forms of glassware, plasticware, reagents and personal protective equipment (PPE) and are used across all scientific laboratories, enabling daily tasks to be performed. Explore a range of flasks and beakers, petri dishes, carboys and storage bottles. Labware such as condensers, desiccators and burettes are also available for more specific tasks. Find the best labware and lab supplies in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Sample ManagementSample management systems include sample storage devices such as freezers and plate storers, sample environment enclosures and sample organization, retrieval and sorter systems. Useful system features include high-throughput, automation, robotic arms, automated liquid handling and associated database systems. Accessories in sample management include barcode scanners, heat sealers and tubes.Assay AssemblyAssay Assembly is technique used in drug discovery to develop assays to test the cytotoxicity, genotoxicity, or other activities of a compound on a cell. Assay assembly requires chip assembly, a delivery system and a detection and analysis method. Beneficial features of assay kits or automated systems include high-throughput, high speed and sensitivity and low signal to noise ratio.Software PlatformsSoftware platforms are useful for various stages of laboratory experiments from data collection to data storage and processing. For instance lab software is available for system control, data management, data analysis and qualification / validation.DNA / RNA QuantificationDetection and quantification of nucleic acids is important in molecular biology, cloning, expression, forensics and clinical diagnostics. Nucleic acids can be detected by labeling with colorimetric, fluorescent or radio labels and using in situ hybridization kits to identify specific sequences. Multiple nucleic acids can be detected and quantified at once using RNA / DNA detection beads or RNA / DNA microarrays. Find the best DNA / RNA Quantification products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.AutomationAutomation in laboratories and manufacturing processes enhances efficiency, precision, and scalability by reducing the need for manual intervention. It plays a critical role in improving productivity, minimizing human error, and accelerating workflows in fields like diagnostics, drug development, and industrial testing. Automation technologies include robotic systems, automated liquid handlers, and process control systems that streamline complex tasks and ensure consistent, reproducible results. Explore our peer-reviewed product directory to discover the best automation solutions, compare options, read user reviews, and get prices directly from manufacturers.DNADeoxyribonucleic Acid (DNA) is the main component of chromosomes and the carrier of genetic information of living organisms. Find out here about PCR, NGS, ChIP-Seq, gel imaging, and many other techniques which can be used for the analysis of DNA.Assay DevelopmentThe process of proving an assay to be sensitive with respect to the target is known as assay development. The assay should be able to characterize novel compounds and measure the potency of these compounds against a validated biological target.UVUltraviolet (UV) light is used in a variety of applications, including disinfection, spectrophotometry, and molecular biology. UV light can damage DNA, making it a powerful tool in sterilization and in studies of mutagenesis and gene repair. Explore UV-related products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.DNA Typing
UV-clear microplates for DNA purity checking