Using Enclosed Point-of-Use Filter to Enhance Quality of API for Kidney Dialysis

Amazon Filters has supplied a leading pharmaceutical company with SupaPore PPG pleated depth filter cartridges to enable them to achieve a safe, enclosed point-of-use filter on their nitrogen gas distribution line used in the production of an Active Pharmaceutical Ingredient (API) for kidney dialysis treatments.

The existing nitrogen filters used in the production facility were in the form of a capsule assembly which was considered a potential risk under current health and safety practices on site. As a consequence, a new set-up was sought which had to be both cost effective and provide safe, high quality filtration in a contained, pressurized housing. Working with the pharmaceutical manufacturer, Amazon Filters designed and manufactured a bespoke 5-inch filter housing fitting directly into the line where the previous capsule filter had been installed. The combination of a bespoke filter housing and a 5µm SupaPore PPG polypropylene filter cartridge proved to be ideal for the application meeting all the clients process demands and satisfying their health and safety audit.

As a leading European manufacturer of both filter cartridges and filter housings, Amazon Filters was already known to the pharmaceutical manufacturer and were trusted to meet the demanding technical specifications of the project. Drawing upon its team of experienced designers and engineers, Amazon Filters was able to quickly produce a design and then manufacture the bespoke filter housing within the specified budget and required time frame for the manufacturer.

SupaPore PPG cartridges have proven effective as a gas pre-filter and polishing filter, and as membrane protection for all liquid processing applications. Manufactured using 100% polypropylene media, drainage layers and hardware, the SupaPore PPG pleated depth filter cartridge offers excellent chemical compatibility across a wide range of liquid processing applications. Its thermal bonded construction ensures minimal extractables and its high filtration efficiency makes it an excellent choice for use in many manufacturing processes.

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