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USC-Olympus partnership in multiscale bioimaging furthers precision medicine

EVIDENT

Olympus imaging systems empower next-generation cancer research at USC’s Ellison Institute

28 May 2020
Georgina Wynne Hughes
Editorial Assistant

Industry news

As a global leader in endoscopy and life science solutions, Olympus has long been committed to promoting awareness of cancer screening, prevention and testing. In this spirit, the company recently forged a partnership with the Lawrence J. Ellison Institute for Transformative Medicine at the University of Southern California (USC). To capture the importance of this initiative, and in anticipation of the grand opening of the Ellison Institute’s new building, Olympus has created a video highlighting the relationship between imaging analysis tools and precision cancer medicine. One focus of the partnership is encouraging projects that engage translational oncology and precision anti-cancer drug screening.

The USC-Olympus Innovation Partnership in Multiscale Bioimaging advances multiscale research into cancer prevention, furthering precision medicine’s role in diagnosis and treatment. The Ellison Institute aims to change the way cancer is treated and prevented by driving transdisciplinary, patient-centered and nimble research programs to shape clinical care. Innovative Olympus technologies will be instrumental in advancing biological imaging.

The partnership is guided by the scientific leadership of two internationally recognized leaders: oncologist and biomedical entrepreneur David Agus, M.D., and optical and imaging researcher Scott Fraser, Ph.D. Together, with their respective teams, they are pioneering the development of new technologies to enable 3D and 4D imaging of single cells, organoids, and tumor ecosystems.

“We view one of our main goals as redefining what’s possible,” said Dr. Fraser. “The work that’s happening in this partnership really enables us to ask questions about cells in their normal environment, guided by the information needed for the best clinical insights.”

Dr. Agus commented, “The idea of using deeper imaging, getting much more detail from the images and using that to better understand what is going on, is powerful. And, so, we now have the ability, through imaging technology, of learning so much more. And it’s a combination of the imaging technology with the ability to interpret that data that I think is going to yield one of the biggest breakthroughs in how we treat and understand cancer.”

“Since Olympus developed its first microscope one hundred years ago, the company has made many advances in imaging technology,” said Julien Sauvagnargues, President of Olympus Corporation of the Americas. “This partnership exemplifies the importance of working closely with scientists to enable groundbreaking research in pathology and cytology. It also draws upon our strengths in visualizing anatomy as we have done in a pioneering manner since the development of the world’s first gastrocamera in 1950. We are honored to be included in this effort to understand some of our most deadly diseases.”

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In Vivo Imaging Systems<i>In vivo</i> imaging systems, including pre-clinical imaging systems and medical imaging systems are used to non-invasively visualize and capture images of live animals and plants. Monitor the natural processes or diseases of your subjects using small-animal pre-clinical imaging systems, including single photon positron emission tomography (SPECT), positron emission tomography (PET), computed tomography (micro-CT), magnetic resonance imaging (MRI), X-ray radiography, ultrasound, fluorescence and bioluminescence imagers. Multimodal systems and software solutions are also available for correlative analysis of organ, tissue, cell, or molecular-level processes. Find the best in vivo imaging products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Light MicroscopyLight microscopes or optical microscopes are used to visualize microscale objects under magnification, including cells, clinical specimens and materials. Lab equipment for light microscopy includes confocal microscopes, fluorescence microscopes, zoom and stereo microscopes. Microscope slides and imaging reagents are available for visualizing samples, as well as various microscope stages and incubators for large or temperature-sensitive samples. Find the best light microscopes in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell ImagingCell imaging can be achieved using a number of techniques including confocal microscopy, transmission electron microscopy, atomic force microscopy, and light sheet microscopy.ImagingImaging techniques are essential for obtaining visual representations of samples to understand structures, processes, and function in biological, chemical, and physical research. These tools range from traditional light microscopy to advanced imaging modalities like MRI and electron microscopy, providing researchers with valuable data for diagnostics, drug discovery, and material analysis. Explore imaging solutions in our peer-reviewed product directory to compare products, check reviews, and get pricing directly from manufacturers.3D Imaging3D imaging technologies allow for the visualization and analysis of three-dimensional structures at high resolution. These systems are used in fields like molecular biology, material science, and medical diagnostics. 3D imaging can be applied to visualize cells, tissues, and organs, providing valuable insights into their structure and function. Browse our peer-reviewed product directory to find the best 3D imaging solutions, compare products, check reviews, and get pricing directly from manufacturers.MicroscopyMicroscopy is a technique used to observe small objects in detail, from cells to materials, using light or electron microscopes. It enables researchers to examine structures with high resolution, aiding in fields such as biology, medicine, and materials science. With advanced microscopy techniques, scientists can gain insights into cellular processes, tissue structures, and material properties. Explore the best microscopy solutions in our peer-reviewed product directory, compare products, read customer reviews, and get pricing directly from manufacturers.BioimagingPrecision MedicinePrecision medicine refers to the idea of customized healthcare, where medical decisions and treatments are tailored to the individual patient. Molecular diagnostics, companion diagnostics and Next Generation Sequencing (NGS) play a pivotal role in this approach. Cancer ResearchAlthough cancer is often referred to as a single condition, it actually consists of more than 100 different diseases. Microscopy, mass spectrometry, high throughput sequencing and flow cytometry are some of the most common techniques employed in cancer research labs.

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USC-Olympus partnership in multiscale bioimaging furthers precision medicine