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UHPLC System Designed to Enhance Many Biopharmaceutical Applications

Thermo Fisher Scientific
30 Jan 2013

Product news

Thermo Fisher Scientific is pleased to introduce the Thermo Scientific™ Dionex™ UltiMate™ 3000 Biocompatible Rapid Separation (BioRS) system, designed to bring highly flexible UHPLC separation capabilities to a wide range of biopharmaceutical research and QA/QC analyses.

The UltiMate 3000 BioRS system has an extensive selection of modules that supports high resolution separations for R&D and also high throughput analyses for QA/QC on the same platform, at pressures up to 15,000 psi. Options include wide selections of pumps, detection techniques, fraction collectors, and autosamplers. The platform is designed for easy method transfer between different stages of pharmaceutical product development and production.

Thermo Fisher Scientific offers dedicated bio UHPLC consumables that help the UltiMate 3000 BioRS system perform quickly and well in a variety of modes, including those requiring harsh solvents. These include gold standard Thermo Scientific™ ProPac WCX protein columns for QA/QC, UHPLC ion-exchange columns, and a wide range of mixed mode and HILIC columns.

Biocompatible capillaries with the Thermo Scientific™ Dionex™ Viper™ Fingertight fitting system are designed for rugged, virtually dead-volume-free connections.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.Quality ControlQuality control is needed in all production processes. Quality control is a monitoring procedure or set of procedures that are put in place to ensure that a manufactured product adheres to a defined set of quality criteria. BiopharmaceuticalsBiopharmaceuticals are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or for in vivo diagnostics. The most well known example of a biopharmaceutical product, and the first to be approved for therapeutic use, was recombinant human insulin.BiopharmaceuticalsBiopharmaceuticals are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or for in vivo diagnostics. The most well known example of a biopharmaceutical product, and the first to be approved for therapeutic use, was recombinant human insulin.BiopharmaceuticalsBiopharmaceuticals are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or for in vivo diagnostics. The most well known example of a biopharmaceutical product, and the first to be approved for therapeutic use, was recombinant human insulin.

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UHPLC System Designed to Enhance Many Biopharmaceutical Applications