U.S. Patent Awarded for Single-Use Bioreactor Design

First of its kind plug-and-play benchtop bioreactor by Distek, Inc., awarded patent

22 Oct 2018
Frankie MacDonald
Administrator / Office Personnel

Product news

Distek, Inc., a leading manufacturer of laboratory testing instruments for the pharmaceutical and biotechnology industry for over 40 years, has been awarded U.S. Patent 10,059,914 for their single-use bioreactor design.

“This patent provides protection for our truly novel design. This invention provides the only true plug and play single use bioreactor for the benchtop market,” says Jeff Watkins, Director of Engineering, Distek, Inc.

Distek’s patented, single-use bioreactor system, also known as the BIOne, embodies a disposable bioreactor including a headplate and a stirrer. The headplate has at least one inlet port aperture and one outlet port aperture formed therein and is adapted to couple sealing with a bag capable of receiving a culture medium. The stirrer is coupled to and extends from the headplate and is adapted to stir the culture medium when the headplate is coupled to the bag. The bioreactor is adapted to fit within the upper opening of the stand of an existing conventional glass bioreactor, so that the bag is suspended within the vessel.

“Our BIOne has sparked great excitement in the industry by filling an important customer need in terms of utilizing a single-use bag solution,” says Jeff Brinker, President. “The acceptance of this patent continues to prove Distek’s commitment to providing innovative solutions for our customers in the biopharma industry.”

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Process ChemistryProcess chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.Bioprocessing / FermentationBioprocessing is the use of biological materials to perform commercial, scientific or medical research processes. Biological materials used include cells, enzymes and organisms. Usually bioprocessing requires a batch or continuous bioreactor such as a fermentor or cell culture system. The advantages of using a reactor include high productivity, easy configuration, adjustable values and automation.
U.S. Patent Awarded for Single-Use Bioreactor Design