TriStar2 – The New and Improved Multimode Plate Reader

16 Oct 2011

Product news

Berthold Technologies announces the launch of the second generation of its successful TriStar multimode plate reader – the TriStar2 LB942. The TriStar2 offers revised optimized optical paths for the reading technologies' absorbance, luminescence and fluorescence. Hence TriStar2 has detection sensitivities known from dedicated instruments. Particularly notable is its new enhanced fluorescence performance.

The TriStar2 is equipped with a universal and low noise detector for fluorescence and luminescence measurements and a photo diode for absorbance reading. Optical emission filters can be used in TriStar´s luminescence and fluorescence optics enabling to measure BRET (e.g. functional assays for GPCR research) and multicolour luciferases (reporter gene assays). TriStar2 can be supplemented with up to 3 reagent injectors – based on the proven and highly precise JET technology – and a temperature control unit for the microplates. Two of the injectors are in measurement position enabling to measure precisely very fast flash reactions.

Furthermore there is a reagent tray at the front of the instrument offering easy access and the possibility to cool injector reservoirs by adding ice. For higher throughput, TriStar2 can be equipped with the Stacker unit LB 931 or be integrated into a laboratory automation system. TriStar2 offers extensive opportunities to its users and a huge variety of application options including the measurement of enzyme kinetics, phagocytosis, calcium flux, cell viability, apoptosis, immunoassays, protein and DNA concentration and protein-protein interactions.

For more information please view the company article page.

Links

Tags

Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Cell Lines Stem Cells and Primary CellsPrimary cell cultures, established cell lines and stem cells are vital for <i>in vitro</i> and <i>ex vivo</i> experimentation. High-quality cells, optimized for your applications, alongside optimized cell substrates, growth medium and supplements, are critical for experimental success. Explore a range of cells suitable for your applications, including isogenic cell lines, competent cells, induced pluripotent stem cell (iPSC)-derived cell lines, fungal/bacterial/mammalian cell lines, stem cells and cancer cell lines. Find the best cells for your research in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Plate ProcessingAutomated plate processing is used in microplate technologies for high-throughput, speed and efficiency. Plate processing systems include microplate handlers for moving plates, heat sealers, stackers and carousels for storage, retrieval and delivery, microplate washers and piercers. Useful features of plate processors include walk-away automation, compatibility and easy integration with microplate systems.