Trends in Analytics: Digitization, Detecting Novel Pollutants and More

23 Mar 2018
Lui Terry
Administrator / Office Personnel

Industry news

From material testing to environmental monitoring: At analytica, companies and research institutions from all over the world present their latest developments. A glance at the key aspects of the international leading trade fair for laboratory technology, analysis and biotechnology shows: Here, trade fair visitors experience technological innovations as well as the latest devices and industry trends.

Susanne Grödl, Exhibition Director of the analytica, on these trends: “The innovative power of the industry is unbroken. And that is a good thing too, because sophisticated analytical methods form the basis for technological progress, in in pharmaceutical research and many other areas. Nowhere are the manufacturers of analytical, bio and laboratory technology demonstrating more clearly than at the analytica that they meet these requirements.”

Whether new tools for evaluating Big Data, or networked devices that can be controlled via app: The digital transformation is inspiring all analytical disciplines from industrial process monitoring to food and environmental monitoring. The analytica 2018 therefore picks up on the megatrend of digitization in a variety of ways. In addition to the successful forums Biotech and Laboratory & Analysis, there is now the Forum Digital Transformation with application-related expert lectures and discussion panels. The handling of rising throughput volumes and the ever-increasing flood of data are likewise unifying themes in the program of the analytica conference.

Material and process analytics: Imaging on the upswing

The trend towards devices that combine various measurement methods is also continuing. Raman imaging in particular is still on the rise. Exhibitors such as WITec and Jasco combine chemical analysis by Raman spectroscopy with optical information from microscopy. Leica Microsystems, on the other hand, provides light microscopy with a module for laser-induced plasma spectroscopy. This also enables imaging and chemical characterization in one step—handy, for example, in particle analysis.

In any case, Raman analyzers are playing an increasingly important role in industrial material and quality control, as they work non-destructively. A Raman spectrometer by B&W Tek analyzes materials even through packaging materials. Renishaw, in turn, has developed a device specifically for the pharmaceutical industry: It combines surface texture analysis with chemical analysis to reveal the distribution of active ingredients and other particles within a tablet. The method is suitable for quality control as well as for development of the optimal formulation of medicines.

For non-contact industrial process and quality control, there is also the relatively young terahertz technique available, which uses radiation in the frequency range between microwaves and infrared light. Terahertz radiation is much lower in energy than X-rays are, and therefore not harmful to health. Nevertheless, it penetrates many non-metallic packaging materials. At the analytica, TOPTICA Photonics will present a terahertz system that rays objects on fast-moving conveyor belts. Among other things, absence of information leaflets in drug packages can thus be recognized.

Detecting novel pollutants

Detecting unknown pollutants instead of just measuring already regulated substances: Food and environmental analysts are increasingly pursuing this goal. At analytica, they will find the complete equipment for so-called non-target analytics and suspect screening—starting with accessories and devices for bioassays, with which adverse effects on the environment and health can be estimated, up to high-resolution mass spectrometers for identification of unknown substances.

An example of chemicals that are currently attracting much attention in both food and environmental analysis are poly- and perfluorinated compounds. They are found in disposable coffee mugs as well as in fire-extinguishing agents and many other products. Measuring them is a challenge, as there are still no reference standards for most members of this large class of substances. The exhibitor a1-environsciences therefore couples high-temperature digestion to ion chromatography and determines organic fluorine compounds as sum parameters. The analytica conference informs about further methods for the analysis of fluorinated substances in a separate session.

Cannabis analytics, neutron imaging, and more

The above novelties show only a small part of the analytica’s wide spectrum. As you walk through the halls, you encounter solutions for all kinds of analytical challenges. For drug analysts, Shimadzu has developed a cannabis analyzer; for life scientists, Thermo Fisher Scientific will present an orbitrap GC-MS system with associated metabolomics library, and for material scientists and archaeologists, the neutron imager at the Photonis booth will be of interest.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Ion ChromatographyIon chromatography, also known as ion exchange chromatography, is a high-performance liquid chromatographic technique used for the separation and identification of ions or polar molecules in a sample, including proteins, nucleotides and amino acids. Equipment includes ion exchange columns, ion exclusion columns, ion chromatography systems, pumps, and detectors. Find the best ion chromatography equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Infrared / IR SpectroscopyInfrared (IR) spectroscopy measures the interaction of infrared light with a sample, including transmission, reflectance & absorbance, facilitating the identification of analytes. Equipment used for quantitative analysis includes Fourier-transform infrared (FTIR) spectrometers, infrared cameras, FTIR gas analyzers, as well as attenuated total reflectance (ATR) accessories and pellet or film presses. Find the best IR spectroscopy products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Near Infrared SpectroscopyNear-infrared (NIR) spectroscopy measures the interaction of near-infrared light with a sample, including transmission, reflectance and absorbance, facilitating the identification of analytes. Measurements can be conducted using a Fourier-transform near infrared (FT-NIR) spectrometer, while there are also UV-Vis- NIR spectrophotometers that measure a broader spectrum of wavelengths. Find the best NIR spectroscopy products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Raman SpectroscopyRaman spectroscopy is used to discern the vibrational and rotational states of molecules and hence the chemical composition of a sample by measuring the inelastic scattering of monochromatic light. Explore a range of Raman spectrometers, including handheld/portable Raman spectrometers for QC/QA labs and in situ spectrometers for processes. Conduct Raman imaging for microanalysis of mixed samples using a Raman microscope. Raman spectrographs are also available. Find the best Raman spectroscopy products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.UV-Visible SpectroscopyUltraviolet-visible (UV-Vis) spectrophotometers are used to measure the interaction of UV and visible light with a sample, including transmission, reflectance & absorbance. The two major instrument classes are single-beam or double-beam spectrophotometers. More specialized equipment includes colorimeters, spectroradiometers and refractometers. Portable and microvolume spectrophotometers are also available. For the modular spectroscopy lab, explore a range of light sources for combination with a spectrograph/spectrometer and optics. Find the best UV-Vis spectroscopy products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Chem / BioinformaticsCheminformatics and bioinformatics are computational techniques used in chemistry and biology, respectively, for data acquisition, processing and storage. Cheminformatics focuses on compound information, whereas bioinformatics is mainly applied to analysis and modeling of genomics, genetic and sequencing information. Hardware and software is available for data acquisition, analysis, management and storage.Data MiningData mining is an important process for extracting information, patterns and trends from data. Data mining software, databases, reference materials and storage packages are available to process lab data.Light MicroscopyLight microscopes or optical microscopes are used to visualize microscale objects under magnification, including cells, clinical specimens and materials. Lab equipment for light microscopy includes confocal microscopes, fluorescence microscopes, zoom and stereo microscopes. Microscope slides and imaging reagents are available for visualizing samples, as well as various microscope stages and incubators for large or temperature-sensitive samples. Find the best light microscopes in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.GC-MS GC-MS (gas chromatography-mass spectrometry) instruments and equipment are used to separate, quantify and identify mixtures of small and volatile compounds, such as polycyclic aromatics, fatty acids and alcohols. Often used in drug detection, forensic investigation and environmental analysis for pesticides and contaminants, GC-MS is a powerful addition to your lab’s analytical capabilities. GC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzers can give greater sensitivity and resolution to your analysis. Find the best GC-MS instruments and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.analyticaAnalytica is a leading international trade fair for laboratory technology, analysis, and biotechnology, showcasing innovations and solutions in the scientific community. Stay updated with the latest trends and products in the industry.