Touch the Future of Gel, Blot and In Vivo Imaging

25 Mar 2012
Roger Wayman
Administrator / Office Personnel

Product news

At AACR this year UVP will be introducing the new ChemiDoc-It®TS2 Imagers which enable quick and simple image capture. The integrated computer, touch screen and exclusive capture software simplify workflow for imaging of chemiluminescent, fluorescent and colorimetric gels and blots. Users can simply click the Live Preview button to immediately see an image sample. The built-in computer creates a networkable, stand-alone system. Researchers can save images to a USB stick or transfer to a network computer for further analysis or documentation.

Users of the new ChemiDoc-ItTS2 can:

• Optimize gel and chemiluminescent blot imaging with the highly sensitive megapixel resolution, cooled CCD camera.
• View low light samples in the light-tight darkroom which creates an optimum environment for chemiluminescent blots.
• Select components as required for specific applications. The modular design allows selection of UV transilluminator, emission filters, LED white light plate, epi UV modules and BioLite MultiSpectral Light Source.

UVP’s BioImaging Systems include the BioSpectrum® Imaging System with the new MegaCam 810 scientific grade CCD camera. Achieve enhanced image capture with the MegaCam 810's dynamic 8.1 megapixel high resolution and high sensitivity capabilities. Not only can researchers capture fluorescence gel images, they can also be assured that camera sensitivity and efficient ultra-cooled technology permits superior capture of chemiluminescent western blots. The system is configured with VisionWorksLS software which allows easy navigation with simple one-touch controls for dynamic capture and extensive quantitative analysis. The automated configuration allows selection of multiple UV, white and blue light sources as well as control of the motorized platform. The emission filters, positioned in a motorized five-position filter tray, include EtBr, SYBR Green and SYBR Gold filters as standard. Additional filters are available. The system capabilities can be expanded to multiplex and bioluminescence imaging by adding a BioLiteTM MultiSpectral Light Source to enable excitation of a wide range of stains.

The iBox® Explorer™ Imaging Microscope enables brilliant resolution macro to micro technology for fluorescence in vivo animal imaging. The iBox Explorer provides breakthrough advances with dual lighting and software-controlled objectives for imaging of tissues, tissue margins and individual cells. With the rapid and multiplexed fluorescence detection of tumor margins and micro metastasis, the iBox Explorer cleanly separates normal from cancer tissues via the cell's fluorescent signature. The system delivers optical configurations that are parcentered and parfocal, allowing seamless imaging through the magnification ranges. The leading-edge cooled CCD camera enables quick detection and high resolution image capture. An integrated computer/touch screen monitor is loaded with the easy to use VisionWorks®LS software. The system features a BioLite™ Xe light source which provides a brilliant illumination source for multispectral fluorescent, visible and NIR excitation. The iBox Explorer is the ideal system for applications including tumor shedding and angiogenesis, micro/macro metastases, tumor/host margins and interactions and primary tumor growth. Additionally, UVP offers the iBox® Scientia Imaging System which detects fluorescent proteins in whole animals for cancer research.

UVP will also feature additional BioImaging Systems including the GelDoc-It® series imagers for high resolution gel imaging and analysis. Select from imagers with a built-in computer/touch screen or an external computer/monitor. Perform basic gel documentation with the BioDoc-It® Imaging System, a compact stand-alone unit with built-in touch screen.

UVP manufactures a large selection of ultraviolet products. The UV lamps feature handheld, high intensity, fixture models and miniature Pen-Ray® Light sources for uses including fluorescence, inspection, analytical and sterilization applications. Ultraviolet products include a large selection of UV transilluminators, UV crosslinkers and UV cabinets plus UV intensity meters for measuring the useful life of a UV source.

UVP products include HEPA/UV PCR hoods and workstations. HEPA systems feature four-stage filter system for eliminating contamination. Precision heated hybridization ovens include the unique HL-2000 HybriLinker features a hybridization oven and UV crosslinker chambers in one unit for maximizing procedures.

Visit booth 712 to learn more.

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Gel Doc / Image AnalysisGel documentation (gel doc) or gel imaging systems are used for the analysis of proteins, antibodies and nucleic acid immobilized in polyacrylamide or agarose gels, membranes or microarrays. Explore a range of a gel imaging systems, densitometers, scanners, transilluminators or UV lamp + CCD cameras for your image analysis solutions. Colorimetric, fluorescent and/or radioisotopic samples can be visualized and documented for further analysis. See gel doc / Image analysis software for quantitative 1D and 2D analysis of your samples. Find the best gel doc / image analysis products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.High-Content ScreeningHigh-content screening (HCS), also known as high-content analysis (HCA), is a high-throughput technique used in drug discovery to identify substances that alter the phenotype of cells. HCS uses fluorescent microscopic imaging and automated image analysis to investigate cellular events such as apoptosis, cell viability, GPCR activation, oxide production, neurite outgrowth, and cell signaling. Find the best fluorescent labeling reagents, cellular assays, and high-content imaging systems in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Clinical TrialsClinical Trials, an essential part of drug discovery process, assess the safety and effectiveness of a new medication or device in the pharmaceutical industry. Clinical Trials are a phased process (Phase 0, Phase I, Phase II, Phase III and Phase IV) which begins after initial preclinical testing.In Vivo Imaging Systems<i>In vivo</i> imaging systems, including pre-clinical imaging systems and medical imaging systems are used to non-invasively visualize and capture images of live animals and plants. Monitor the natural processes or diseases of your subjects using small-animal pre-clinical imaging systems, including single photon positron emission tomography (SPECT), positron emission tomography (PET), computed tomography (micro-CT), magnetic resonance imaging (MRI), X-ray radiography, ultrasound, fluorescence and bioluminescence imagers. Multimodal systems and software solutions are also available for correlative analysis of organ, tissue, cell, or molecular-level processes. Find the best in vivo imaging products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Light MicroscopyLight microscopes or optical microscopes are used to visualize microscale objects under magnification, including cells, clinical specimens and materials. Lab equipment for light microscopy includes confocal microscopes, fluorescence microscopes, zoom and stereo microscopes. Microscope slides and imaging reagents are available for visualizing samples, as well as various microscope stages and incubators for large or temperature-sensitive samples. Find the best light microscopes in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.AACRThe American Association for Cancer Research (AACR) is a leading organization focused on cancer research and treatment. It provides a platform for scientists, healthcare professionals, and industry leaders to share knowledge and collaborate in the fight against cancer.Bioimaging
Touch the Future of Gel, Blot and In Vivo Imaging