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Top methods and technologies advancing the field of mass spectrometry

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Explore exclusive interviews, methods, and free downloads to help you optimize your mass spectrometry experiments

13 Oct 2020
Diane Li
Assistant Editor

Editorial article

Our exclusive Advances in Mass Spectrometry special feature is now live! We’ve compiled a list of the latest technologies and techniques as well as free downloads to help you maximize lab productivity. Read on to learn how to achieve targeted peptide quantification with LC/MS, take a look inside a cutting-edge forensics lab, find out how LC/MS/MS is optimizing clinical testing, and discover the benefits of ion detection technology.

Biomarkers: Achieve targeted peptide quantification with LC/MS

This application note teaches you how to precisely quantify protein biomarkers in biological fluids using the 6495C triple quadrupole LC/MS system from Agilent.

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Guilty or not guilty? Inside a cutting-edge forensic lab

Discover how Agilent is helping forensic experts at LAT LUMTOX analyze the evidence and take a leading role against crime with a range of equipment designed to provide full-spectrum accurate-mass data.

Download method

Diagnostics: LC-MS/MS for optimized clinical testing

Consultant clinical scientist Dr. Emma Walker reveals how collaboration with Waters helped ensure her lab's smooth transition from immunoassays to LC-MS/MS and more effective diagnostic services.

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LC/MS & GC/MS: Accelerate deformulation to streamline characterization

Discover the two-step approach from ACD Labs using a newly updated spectral searching workflow to effectively expedite the simultaneous deformulation of multiple components and streamline characterization.

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Ion detection: Productivity, performance and profit

Discover how ion detection technology can help you increase productivity, solve analytical challenges and maximize profit using eXtion Electron Multipliers from Adaptas with reduced run times, sample prep and cost.

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Run fast: Get analysis speeds of up to 3 samples per second

Discover the Echo® MS System. An ultra-high sample throughput for Acoustic Ejection Mass Spectrometry from SCIEX, delivering speed, scale and reproducibility with unyielding data quality up to 50X faster than conventional LC-MS/MS.

Watch video

eBook: How to buy LC/MS technology for life sciences

Download our free eBook to discover the key factors and application considerations when looking to buy LC-MS technology to help you find the best solutions for your lab.

Download eBook

Expert insights:

  • Prof. Ian Wilson, Imperial College London, and Prof. Kostas Thalassinos, University College London, highlight the benefits of ion mobility mass spectrometry for life sciences research. Watch webinar>>
  • Dr. Mark Perkins, Anatune, and Dr. Vaughan Langford, Syft Technologies, discuss how selected ion flow tube mass spectrometry (SIFT-MS) works, how it speeds up analysis, and how it can be validated successfully in accordance ICH Q2(R1) Guidelines. Watch webinar>>
  • Prof. Zoltan Takats, Imperial College London, explores the applications and benefits of ambient ionization for biomedical research and its future potential for pharma and food industries. Watch webinar>>
  • Dr. Chris Petucci, University of Pennsylvania, explains how his lab performs targeted and untargeted LC/MS metabolomics for internal and external research investigators and industry. Watch webinar>>

Other resources:

  • SCIEX provides an overview of the key features of its Triple Quad™ 7500 LC-MS/MS System – QTRAP® Ready. Watch video>>
  • Learn about novel approaches to brain research in this exclusive interview with Prof. Jonathan Sweedler, University of Illinois. Watch video>>
  • Learn about the advantages of the StreamSelect LC/MS solution, designed for boosting lab productivity using innovative flow path design and software contol. Download method>>
  • Achieve rapid identification of potential disease biomarkers in breath, through the use of sampling onto TD tubes, followed by automated preconcentration and GC-TOF MS. Download method>>

Top news stories in mass spectrometry

  • Thermo Fisher's new LC-MS workstream offers a comprehensive solution for toxicology. Learn more>>
  • Peak Scientific introduces new gas generator and bench solutions for the SCIEX 7500 LC-MS system. Learn more>>
  • Cerno Bioscience releases latest version of its mass spec software. Learn more>>

Your recommendations:

Take a look at what other researchers and scientists all over the world are saying about the latest equipment and technologies in mass spectrometry. Raj Kumar, Punjab University, shared their opinion on the Thermo Scientific™ TSQ™ 9000 Triple Quadrupole GC-MS/MS System.

Find more news and resources in our dedicated Advances in Mass Spectrometry Special Feature>>

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LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. MALDI-TOF MSMALDI-TOF mass spectrometers (matrix-assisted laser desorption/ionization time-of-flight) are used for the mass analysis of large molecules, including proteins, DNA, polymers and other macromolecules due to its relatively soft ionization, reducing fragmentation whilst allowing fast data acquisition. Tandem mass analyzers such as TOF/TOF systems can be used to increase resolution and sensitivity of your analysis. Find the best MALDI-TOF products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.GC-MS GC-MS (gas chromatography-mass spectrometry) instruments and equipment are used to separate, quantify and identify mixtures of small and volatile compounds, such as polycyclic aromatics, fatty acids and alcohols. Often used in drug detection, forensic investigation and environmental analysis for pesticides and contaminants, GC-MS is a powerful addition to your lab’s analytical capabilities. GC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzers can give greater sensitivity and resolution to your analysis. Find the best GC-MS instruments and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ImmunoassayImmunoassays are laboratory tests that utilize antibody-antigen interactions to detect specific substances. They are widely used in diagnostics for detecting diseases, drug testing, and environmental monitoring. These assays offer rapid, sensitive, and precise detection of biomarkers, making them invaluable in clinical and research labs. Browse our peer-reviewed product directory to compare immunoassay systems, read user reviews, and get pricing directly from manufacturers.Triple Quadrupole MsICP-MSInductively Coupled Plasma Mass Spectrometry (ICP-MS) is a powerful analytical technique used to determine the concentrations of elements and their isotopes in a variety of samples, including water, soil, and biological tissues. It involves ionizing elements in the samples with extremely high-temperature Argon (Ar) plasma and then using a mass spectrometer to measure the number of ions based on their mass-to-charge ratio (m/z). Explore ICP-MS systems in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Clinical Mass SpectrometryMass spectrometry is emerging as a superior method of analysis over the longstanding, gold standard of immunoassay. Clinical mass spectrometry systems are increasingly accessible to medical laboratories and are capable of providing results with more speed and less expense than traditional methods. From simple mass spectrometers to IVDR class A compliant, highly sophisticated systems performing liquid chromatography tandem mass spectrometry (LC/MS/MS), find the latest product news, reviews and resources to make a purchasing decision for your laboratory. Forensic ToxicologyForensic toxicology is used to determine cause of death, drug use and contaminations. Toxicological evaluations are commonly used in analytical chemistry, clinical, life sciences and forensics.Imaging Mass SpectrometryGC-MSGas Chromatography-Mass Spectrometry (GC-MS) combines the separation power of gas chromatography with the detection capabilities of mass spectrometry, allowing for the analysis of complex mixtures. It is widely used in environmental, forensic, and pharmaceutical analysis. Explore GC-MS systems in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.

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