Tissue dissociation and animal model reagents

Enzyme Explorer Tool from Merck enables you to select the optimum enzyme for your tissue dissociation or cell detachment needs

5 Nov 2021
Blake Forman
Content Creator

Industry news

When determining the best tissue dissociation and animal model reagents for your workflow needs, it is critical to have the best reagent that reliably delivers the results you can count on. Merck’s comprehensive offering of enzymes, protein reagents and kits are well characterized with lot-to-lot consistency. Merck’s comprehensive offering and rigorous quality standards provide you with the confidence that you will always receive consistent, high-quality reagents for your small-scale or bulk size needs.

Additionally, Merck provides consistent, reliably supplied extraction and fermentation-based enzymes available at the manufacturing scale under GMP. Whether you require products for research or life science manufacturing needs, our tissue dissociation and animal model reagent offerings provide convenience, stability, robust lot sizes, and customization flexibility. Altogether, these benefits are suitable for use in the manufacturing of assays, ELISA, blotting, and additional kit types.

Efficient tissue dissociation depends on numerous factors, including how the tissue was dissected, tissue age, and the quality or blends of your tissue dissociation enzymes. Select the ideal enzyme using Merck’s Enzyme Explorer Tool for your cell detachment or tissue dissociation needs, including trypsin, collagenase, papain, nucleases, hyaluronidase, and elastase. As a global distributor, Merck’s reliable and secure supply chain ensures that you will have the optimal tissue dissociation and animal model reagents when your research and lab product manufacturing work requires them.

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ELISAEnzyme-linked immunosorbent assays (ELISA), also known as enzyme immunoassays (EIA), are used for the detection and quantification of proteins, peptides and antibodies in a sample. ELISA often comes in kit format, with pre-selected antibody pairs to detect specific proteins or biomarkers of diseases such as diabetes and obesity, or cardiovascular and neurological disorders. Detection is made possible with chemiluminescent, fluorescent or colorimetric substrates and detection instruments such as microplate / ELISA readers. Other kits available include: Enzyme-linked immunospot (ELISPOT) assays for the quantification of protein-producing cells and chemiluminescent immunoassays (CLIA) kits. Find the best ELISA kits and products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Animal ModelsThe use of non-human animals in experiments or behavorial observations. The research is conducted inside universities, medical schools, pharmaceutical companies, farms, defence establishments, and commercial facilities that provide animal-testing services to industry. It includes pure research such as genetics, developmental biology, behavioral studies, as well as applied research such as pharmaceutical testing in pre-clinical, before human, studies. EnzymesEnzymes are macromolecular biological catalysts used across life science, pharmaceutical and clinical research. Various enzymes can be purchased for research applications including ligases, high fidelity polymerases, nuclease, protease, restriction enzymes, tissue dissociation enzymes and enzyme inhibitors. Find the best enzymes in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Tissue ProcessingTissue processing involves preparing biological tissue samples for microscopic analysis, including fixation, embedding, and sectioning. This process is essential for histopathology and diagnostic applications. Explore tissue processing products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Cell Based AssaysCell-based assays use living cells to measure biological responses to various treatments or stimuli. They are essential for drug discovery, toxicology testing, and understanding cellular mechanisms. These assays are used to assess cell viability, proliferation, gene expression, and other cellular activities. Browse our peer-reviewed product directory to find the best cell-based assay tools and reagents, compare products, read customer reviews, and get pricing directly from manufacturers.ELISA