Thomson Reuters and ChemAxon Partner to Help Speed Drug Discovery for Life Science Researchers

5 Jan 2011
Sarah Sarah
Marketing / Sales

Product news

Thomson Reuters is providing its chemical IP Data Feeds – Markush Structures and patent data to users of ChemAxon’s JChem chemical software platform. This search and analysis solution will speed drug discovery and allow life science researchers to easily integrate critical content into their existing systems and workflow.

The Markush structures from Thomson Reuters are part of the company’s Derwent World Patents Index® (DWPISM) database, the world’s most trusted and authoritative source of global patent information. The Markush database contains essential data on the relationship or “families” of 550,000 patents, making it the world’s leading source for life sciences patentability research, competitive intelligence and IP screening. ChemAxon’s JChem software allows life science professionals to structure and visualize chemical compounds for property prediction, virtual synthesis, screening and drug design. Through this partnership R&D end users can now research and analyze Markush structures using ChemAxon’s JChem chemical software platform, a means they had no access to before. The ability to quickly retrieve this information will now allow R&D end users to save time and capitalize on R&D investment.

“The ability to search and visualize complex chemical patents is critical to the work of life science R&D professionals. To date, however, this has been a challenge as there wasn’t a tool that enabled R&D end users to do this type of work themselves,” said Cindy Poulos, vice president of product management, Thomson Reuters. “Through this partnership, Thomson Reuters and ChemAxon are making a comprehensive worldwide database of chemical compounds widely accessible in a user-friendly, flexible format to end users.”

“The Markush structures database has become a vital backbone of pharmaceutical research in the digital age,” said Alex Drjver, CEO of ChemAxon. “By delivering this data directly to the end user in an intuitive, flexible format, our clients have access to the functionality and data necessary to stay competitive in today’s fast-paced, complex marketplace.”

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High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Chem / BioinformaticsCheminformatics and bioinformatics are computational techniques used in chemistry and biology, respectively, for data acquisition, processing and storage. Cheminformatics focuses on compound information, whereas bioinformatics is mainly applied to analysis and modeling of genomics, genetic and sequencing information. Hardware and software is available for data acquisition, analysis, management and storage.High-Content ScreeningHigh-content screening (HCS), also known as high-content analysis (HCA), is a high-throughput technique used in drug discovery to identify substances that alter the phenotype of cells. HCS uses fluorescent microscopic imaging and automated image analysis to investigate cellular events such as apoptosis, cell viability, GPCR activation, oxide production, neurite outgrowth, and cell signaling. Find the best fluorescent labeling reagents, cellular assays, and high-content imaging systems in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.