Thermo Fisher Scientific Unveils New Line of TurboFlow<sup>®</sup> Columns for Use with its Transcend™ Chromatography Systems

3 Jun 2007

Product news

Thermo Fisher Scientific Inc., the world leader in serving science, introduces a new line of silica-based TurboFlow® columns designed exclusively for use with Thermo Scientific Transcend™ Systems.

The columns provide scientists in clinical research and pharmaceutical analysis the capability to integrate online sample preparation with LC-MS analysis. The TurboFlow XL columns — a new line of Thermo Scientific columns incorporating patented TurboFlow technology — enable researchers to reduce sample preparation time and minimize ion suppression, while providing faster analysis and more confident data. The TurboFlow XL columns will be displayed in booth #57 at the 55th Annual ASMS Conference on Mass Spectrometry in Indianapolis, Indiana, June 3-7, 2007.

The expanded breadth of the new TurboFlow XL columns will provide a greater selection of column chemistries and tools for developing TurboFlow technology methods. TurboFlow XL columns are available in a variety of chemistries — including C18, C8, Fluoro, Phenyl and C2 — and in dimensions of 0.5 and 1.0 mm, which are ideally suited for online sample preparation methods.

Additionally, TurboFlow XL columns are compatible with the Thermo Scientific Aria™ TLX Systems, which use turbulent flow chromatography to separate analytes from biological fluids prior to LC-MS analysis.

TurboFlow technology assists pharmaceutical researchers in reducing matrix effects by retaining small molecules, excluding proteins and larger materials by diffusion, size exclusion and column chemistry. This enables users to directly inject biological samples into the LC-MS/MS system for analysis, a significant advantage in discovery, development, and clinical research, where extensive sample preparation of large numbers of samples is time-consuming and costly.

For more information on the Thermo Scientific TurboFlow XL columns, please visit booth #57 at ASMS, Indiana, June 3-7.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
Thermo Fisher Scientific Unveils New Line of TurboFlow<sup>®</sup> Columns for Use with its Transcend™ Chromatography Systems