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Thermo Fisher Scientific to Show Integrated Proteomic Sample Preparation Workflow at HUPO 2008

28 Jul 2008

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Thermo Fisher Scientific Inc., the world leader in serving science, will introduce an integrated proteomic sample preparation workflow based on the Thermo Scientific KingFisher® Flex magnetic particle processor at HUPO, Amsterdam (August 16-20 2008). Optimized purification protocols and high-speed, automated operation mean that the KingFisher Flex can process an entire 96 well plate in 20-40 minutes. This allows high volume samples to be purified with excellent reproducibility and quality. Full integration with specialized affinity supports provides turn-key solutions for complex purification protocols, greatly reducing assay variability and hands-on time.

The 24-magnet head of the Thermo Scientific KingFisher Flex enables the high-speed processing of 200 – 5000 µL samples in 24-well deep well plates, providing five times the yield with high quality, dependable results. Furthermore, the larger combined volume range (20 – 5000 µL) of the KingFisher Flex makes it suitable for any researchers requiring larger volumes of starting material.

The easy-to-use control panel, color display and on-board memory of the KingFisher Flex ensure instant access to all settings and more than 100 protocols. For more streamlined workflows, the robot-compatible KingFisher Flex integrates smoothly with benchtop automation systems. The inbuilt heating block enables samples to be heated from 4ºC above ambient to 96ºC, for purifications where higher temperatures are required. The KingFisher Flex offers very fast purification of all samples, requiring the minimum amount of hands-on operation and preparation time. Furthermore, the BindIt™ PC interface software lets users easily set access control levels and offers clear reporting and advanced protocol management. These features make the KingFisher Flex ideal for all life science, biotechnology and pharmaceutical research laboratories requiring high throughput proteomic analysis.

For more information about the Thermo Scientific KingFisher Flex, please visit the article webpage.

Thermo Scientific is part of Thermo Fisher Scientific, the world leader in serving science.

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Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.DNA / RNA Extraction and PurificationPurified DNA and RNA are required for numerous downstream molecular biology applications. Consequently, the importance of high-quality DNA/RNA extraction and purification equipment cannot be underestimated. Many purification kits are available and are typically optimized for nucleic acid type and source, including plasmid DNA, genomic DNA, mRNA, RNA and viral nucleic acid purification kits. Automated extraction and purification of nucleic acids can be implemented with magnetic bead separator instruments or high-throughput purification workstations. Find the best DNA/RNA extraction and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Robotic InstrumentsRobotic instruments can be used for high-throughput automation of many lab processes. Such processes use instruments for assays like cell based assays and ELISA, for sample preparation like shakers, centrifuges and incubators, and for analysis such as sequencing and western blot analyzers. Useful features of robotic instruments include speed, reproducibility, barcode readers, software and automation.

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Thermo Fisher Scientific to Show Integrated Proteomic Sample Preparation Workflow at HUPO 2008