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Thermo Fisher Scientific Strengthens Life Sciences Leadership with New Instruments Launched at ASMS 2016

Thermo Fisher Scientific

Thermo Fisher Scientific host a series of informative breakfast seminars for ASMS attendees

6 Jun 2016
Weylan Kiam-Laine
Microbiologist

Product news

Thermo Fisher Scientific Inc., the world leader in serving science, strengthened its industry-leading analytical instruments platform with innovative systems designed to help pharmaceutical and biologics producers more efficiently discover and develop candidate drugs. These new products will be on display at the 64th Annual American Society for Mass Spectrometry (ASMS) Conference, June 5-9 in Texas Ballroom D at the Grand Hyatt Hotel.

“The success of our innovation strategy is based on continuous collaboration with our customers,” said Marc N. Casper, president and chief executive officer Thermo Fisher Scientific. “Our mission is to enable our customers to make the world healthier, cleaner and safer, and we are committed to providing them with the most advanced analytical technologies to help them facilitate research and accelerate discovery. This year’s ASMS showing is another great example of how we continue to leverage our technology leadership to raise the performance bar and help our customers achieve their goals.”

The new Thermo Scientific Q Exactive BioPharma MS/MS Hybrid Quadrupole-Orbitrap mass spectrometer takes full advantage of the high-resolution, accurate-mass (HRAM) capabilities of the Orbitrap mass analyzer to enable key workflows for protein characterization in a single instrument. Combined with recommended sample preparation and analysis methods using Thermo Scientific reagents, columns, UHPLC and data processing technologies, the Q Exactive BioPharma system provides a comprehensive solution for customers performing biopharmaceutical characterization.

At ASMS, Thermo Fisher will also feature its new Thermo Scientific Vanquish Flex Binary UHPLC system, an ideal complement for pharmaceutical and biopharmaceutical laboratories performing qualitative and quantitative LC or LC-MS analysis. Built for high-speed and fast gradient applications, the Vanquish platform delivers outstanding reproducibility.

As part of its focus on innovation, Thermo Fisher will feature new technology from 908 Devices, a pioneer in purpose-built analytical devices for chemical analysis. Customers using Thermo Fisher’s mass spectrometers can now incorporate 908 Devices’ breakthrough ZipChip microfluidics separation technology to deliver fast, high-quality separations that transform analysis of biomolecules.

Thermo Fisher will also showcase high-profile collaborations through presentations and posters by notable scientists doing breakthrough work with its mass spectrometry technologies.

  • Dr. Willi Haas, assistant professor at Harvard Medical School, will present the Advances in Accurate, High-Throughput Quantitative Proteomics Breakfast Workshop. His approach combines Orbitrap HRAM MS and synchronous precursor selection (SPS)-based MS3 technology on the Thermo Scientific Orbitrap Tribrid MS system to accurately measure the smallest changes in low-abundance proteins.

  • Dr. Fan Liu from the Albert Heck Lab, Utrecht University, Netherlands, will present the Improved Workflows for Structural Proteomics Breakfast Workshop. Dr. Liu‘s lab is using Orbitrap technology for proteome-wide cross-linking mass spectrometry to chart the cellular interactome, the whole set of molecular interactions in a single cell.

  • Dr. Jennifer Abelin from the Eli and Edythe L. Broad Institute of MIT and Harvard will present High-throughput Profiling of HLA Allele-specific Peptides by MS for Improved Epitope Predictions at the Thermo Fisher Annual User Meeting She will discuss her use of LC-MS/MS techniques to improve the understanding of antigen processing to identify peptides in diseases including cancer, inflammatory bowel disease and infectious diseases.

  • Dr. Akhilesh Pandey, John Hopkins University School of Medicine, will present Getting Ready for Clinical Proteomics at the Thermo Fisher Annual User Meeting. Dr. Pandey will discuss the emerging use of proteomics in a clinical setting. Dr. Pandey is best known for his groundbreaking research in the mapping of the human proteome.

Finally, Thermo Fisher will recognize the winners of the 2016 Thermo Scientific Tandem Mass Tag (TMT) Research Awards, an international research grant for scientists and their work in proteomics.

Thermo Fisher will be exhibiting in Booth 319 at the Henry B. Gonzalez Convention Center and in Texas Ballroom D at the Grand Hyatt Hotel in San Antonio.

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Thermo Fisher ScientificCompany website

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Bioprocessing / FermentationBioprocessing is the use of biological materials to perform commercial, scientific or medical research processes. Biological materials used include cells, enzymes and organisms. Usually bioprocessing requires a batch or continuous bioreactor such as a fermentor or cell culture system. The advantages of using a reactor include high productivity, easy configuration, adjustable values and automation.Triple Quadrupole MsHigh ThroughputHigh throughput experiments allow the simultaneous processing of several samples. This parallelization reduces the cost per experiment and increases reproducibility and output volume of data.MicrofluidicsMicrofluidics is the science of manipulating small volumes of fluids in micro-sized channels. It is widely used in diagnostics, drug development, and lab-on-a-chip technologies. Microfluidic devices can enable rapid, cost-effective, and high-throughput analysis of biological samples. Browse our peer-reviewed product directory to find the best microfluidic devices, compare products, check reviews, and get pricing directly from manufacturers.BiopharmaceuticalsBiopharmaceuticals are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or for in vivo diagnostics. The most well known example of a biopharmaceutical product, and the first to be approved for therapeutic use, was recombinant human insulin.ProteomicsProteomics refers to the analysis of proteins through a variety of different experiments in order to understand structure and functionality. Typical techniques include protein purification and mass spectrometry. Drug DiscoveryDrug discovery is the process of identifying potential new medications, involving stages such as target identification, compound screening, and preclinical development. It relies on cutting-edge technologies like high-throughput screening, artificial intelligence, and molecular modeling to accelerate the identification of drug candidates. Drug discovery plays a pivotal role in developing new therapies for diseases ranging from cancer to rare genetic disorders. Browse our peer-reviewed product directory to find the latest drug discovery technologies, compare options, check customer feedback, and get pricing directly from manufacturers.BiologicsBiologics are medical products derived from living organisms, including vaccines, gene therapies, and monoclonal antibodies. These treatments are key to modern healthcare, especially in oncology and autoimmune diseases. Explore biologics research tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.LC-MSASMSThe American Society for Mass Spectrometry (ASMS) is an organization dedicated to advancing the science and application of mass spectrometry. ASMS supports professionals through events, publications, and research initiatives, promoting innovation in areas like proteomics, metabolomics, and environmental analysis. Inflammatory Diseases

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